Publications
The structure, binding and function of a Notch transcription complex involving RBPJ and the epigenetic reader protein L3MBTL3.. Nucleic Acids Res. 50, 13083-13099
(2022) Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition. Sci Rep. 12, 9028
(2022) A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 10.1021/acs.jmedchem.1c01779
(2022) tRNA Fusion to Streamline RNA Structure Determination: Case Studies in Probing Aminoacyl-tRNA Sensing Mechanisms by the T-Box Riboswitch. doi:10.3390/cryst12050694
(2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
(2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
(2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
(2022) (2022) 4-Methyl-1,2,3-Triazoles as -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity. J Med Chem. 64, 10497-10511
(2021) Actinobacillus utilizes a binding-protein dependent ABC transporter to acquire the active form of Vitamin B. J Biol Chem. 10.1016/j.jbc.2021.101046
(2021) Allosteric MEK inhibitors act on BRAF/MEK complexes to block MEK activation. Proc Natl Acad Sci U S A. 10.1073/pnas.2107207118
(2021) Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J Virol. 95, e0186820
(2021) Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices. Protein Sci. 10.1002/pro.4268
(2021) Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics (Basel). 10.3390/antibiotics10040390
(2021) Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics (Basel). 10.3390/antibiotics10040390
(2021) Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics (Basel). 10.3390/antibiotics10040390
(2021) A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders. Eur J Med Chem. 219, 113435
(2021) A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders. Eur J Med Chem. 219, 113435
(2021) (2021) CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope. J Exp Med. 10.1084/jem.20210785
(2021) CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells. Neuron. 10.1016/j.neuron.2021.05.007
(2021) CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells. Neuron. 10.1016/j.neuron.2021.05.007
(2021) Crystal structure of a thermophilic fungal cyanase and its implications on the catalytic mechanism for bioremediation. Sci Rep. 11, 277
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