Publications

Found 957 results
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2021
Gu, W., Gao, S., Wang, H., Fleming, K. D., Hoffmann, R. M., Yang, J. Won, Patel, N. M., Choi, Y. Mi, Burke, J. E., Reue, K., and Airola, M. V. (2021) The middle lipin domain adopts a membrane-binding dimeric protein fold. Nat Commun. 12, 4718
Rapp, M., Guo, Y., Reddem, E. R., Yu, J., Liu, L., Wang, P., Cerutti, G., Katsamba, P., Bimela, J. S., Bahna, F. A., Mannepalli, S. M., Zhang, B., Kwong, P. D., Huang, Y., Ho, D. D., Shapiro, L., and Sheng, Z. (2021) Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. Cell Rep. 10.1016/j.celrep.2021.108950
Rapp, M., Guo, Y., Reddem, E. R., Yu, J., Liu, L., Wang, P., Cerutti, G., Katsamba, P., Bimela, J. S., Bahna, F. A., Mannepalli, S. M., Zhang, B., Kwong, P. D., Huang, Y., Ho, D. D., Shapiro, L., and Sheng, Z. (2021) Modular basis for potent SARS-CoV-2 neutralization by a prevalent VH1-2-derived antibody class. Cell Rep. 10.1016/j.celrep.2021.108950
Wang, J., Vaddadi, N., Pak, J. S., Park, Y., Quilez, S., Roman, C. A., Dumontier, E., Thornton, J. W., Cloutier, J. - F., and zkan, E. Ö. (2021) Molecular and structural basis of olfactory sensory neuron axon coalescence by Kirrel receptors. Cell Rep. 37, 109940
Mulvaney, K. M., Blomquist, C., Acharya, N., Li, R., Ranaghan, M. J., O'Keefe, M., Rodriguez, D. J., Young, M. J., Kesar, D., Pal, D., Stokes, M., Nelson, A. J., Jain, S. S., Yang, A., Mullin-Bernstein, Z., Columbus, J., Bozal, F. K., Skepner, A., Raymond, D., LaRussa, S., McKinney, D. C., Freyzon, Y., Baidi, Y., Porter, D., Aguirre, A. J., Ianari, A., McMillan, B., and Sellers, W. R. (2021) Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol Cell. 81, 3481-3495.e7
Mulvaney, K. M., Blomquist, C., Acharya, N., Li, R., Ranaghan, M. J., O'Keefe, M., Rodriguez, D. J., Young, M. J., Kesar, D., Pal, D., Stokes, M., Nelson, A. J., Jain, S. S., Yang, A., Mullin-Bernstein, Z., Columbus, J., Bozal, F. K., Skepner, A., Raymond, D., LaRussa, S., McKinney, D. C., Freyzon, Y., Baidi, Y., Porter, D., Aguirre, A. J., Ianari, A., McMillan, B., and Sellers, W. R. (2021) Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol Cell. 81, 3481-3495.e7
Mulvaney, K. M., Blomquist, C., Acharya, N., Li, R., Ranaghan, M. J., O'Keefe, M., Rodriguez, D. J., Young, M. J., Kesar, D., Pal, D., Stokes, M., Nelson, A. J., Jain, S. S., Yang, A., Mullin-Bernstein, Z., Columbus, J., Bozal, F. K., Skepner, A., Raymond, D., LaRussa, S., McKinney, D. C., Freyzon, Y., Baidi, Y., Porter, D., Aguirre, A. J., Ianari, A., McMillan, B., and Sellers, W. R. (2021) Molecular basis for substrate recruitment to the PRMT5 methylosome. Mol Cell. 81, 3481-3495.e7
Borowska, M. T., Drees, C., Yarawsky, A. E., Viswanathan, M., Ryan, S. M., Bunker, J. J., Herr, A. B., Bendelac, A., and Adams, E. J. (2021) The molecular characterization of antibody binding to a superantigen-like protein from a commensal microbe. Proc Natl Acad Sci U S A. 10.1073/pnas.2023898118
Patchett, S., Lv, Z., Rut, W., Békés, M., Drag, M., Olsen, S. K., and Huang, T. T. (2021) A molecular sensor determines the ubiquitin substrate specificity of SARS-CoV-2 papain-like protease. Cell Rep. 36, 109754
Zhang, C. - H., Spasov, K. A., Reilly, R. A., Hollander, K., Stone, E. A., Ippolito, J. A., Liosi, M. - E., Deshmukh, M. G., Tirado-Rives, J., Zhang, S., Liang, Z., Miller, S. J., Isaacs, F., Lindenbach, B. D., Anderson, K. S., and Jorgensen, W. L. (2021) Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. ACS Med Chem Lett. 12, 1325-1332
Rietmeijer, R. A., Sorum, B., Li, B., and Brohawn, S. G. (2021) Physical basis for distinct basal and mechanically gated activity of the human K channel TRAAK. Neuron. 10.1016/j.neuron.2021.07.009
Landor, S. K. J., Santio, N. M., Eccleshall, W. B., Paramonov, V. M., Gagliani, E. K., Hall, D., Jin, S. - B., Dahlström, K. M., Salminen, T. A., Rivero-Müller, A., Lendahl, U., Kovall, R. A., Koskinen, P. J., and Sahlgren, C. (2021) PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion. J Biol Chem. 10.1016/j.jbc.2021.100593
Cerutti, G., Guo, Y., Zhou, T., Gorman, J., Lee, M., Rapp, M., Reddem, E. R., Yu, J., Bahna, F., Bimela, J., Huang, Y., Katsamba, P. S., Liu, L., Nair, M. S., Rawi, R., Olia, A. S., Wang, P., Zhang, B., Chuang, G. - Y., Ho, D. D., Sheng, Z., Kwong, P. D., and Shapiro, L. (2021) Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe. 10.1016/j.chom.2021.03.005
Cerutti, G., Guo, Y., Zhou, T., Gorman, J., Lee, M., Rapp, M., Reddem, E. R., Yu, J., Bahna, F., Bimela, J., Huang, Y., Katsamba, P. S., Liu, L., Nair, M. S., Rawi, R., Olia, A. S., Wang, P., Zhang, B., Chuang, G. - Y., Ho, D. D., Sheng, Z., Kwong, P. D., and Shapiro, L. (2021) Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe. 10.1016/j.chom.2021.03.005
Cerutti, G., Guo, Y., Zhou, T., Gorman, J., Lee, M., Rapp, M., Reddem, E. R., Yu, J., Bahna, F., Bimela, J., Huang, Y., Katsamba, P. S., Liu, L., Nair, M. S., Rawi, R., Olia, A. S., Wang, P., Zhang, B., Chuang, G. - Y., Ho, D. D., Sheng, Z., Kwong, P. D., and Shapiro, L. (2021) Potent SARS-CoV-2 neutralizing antibodies directed against spike N-terminal domain target a single supersite. Cell Host Microbe. 10.1016/j.chom.2021.03.005
McCarthy, K. R., Lee, J., Watanabe, A., Kuraoka, M., Robinson-McCarthy, L. R., Georgiou, G., Kelsoe, G., and Harrison, S. C. (2021) A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. mBio. 12, e0114421
Castel, P., Dharmaiah, S., Sale, M. J., Messing, S., Rizzuto, G., Cuevas-Navarro, A., Cheng, A., Trnka, M. J., Urisman, A., Esposito, D., Simanshu, D. K., and McCormick, F. (2021) RAS interaction with Sin1 is dispensable for mTORC2 assembly and activity. Proc Natl Acad Sci U S A. 10.1073/pnas.2103261118
LoVerde, P. T., Alwan, S. N., Taylor, A. B., Rhodes, J., Chevalier, F. D., Anderson, T. Jc, and McHardy, S. F. (2021) Rational approach to drug discovery for human schistosomiasis. Int J Parasitol Drugs Drug Resist. 16, 140-147
Roman, C., Lewicka, A., Koirala, D., Li, N. - S., and Piccirilli, J. A. (2021) The SARS-CoV-2 Programmed -1 Ribosomal Frameshifting Element Crystal Structure Solved to 2.09 Å Using Chaperone-Assisted RNA Crystallography.. ACS Chem Biol. 10.1021/acschembio.1c00324
Wybenga-Groot, L. E., Tench, A. J., Simpson, C. D., St Germain, J., Raught, B., Moran, M. F., and C McGlade, J. (2021) SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function. J Mol Biol. 433, 166880
Olenginski, G. M., Piacentini, J., Harris, D. R., Runko, N. A., Papoutsis, B. M., Alter, J. R., Hess, K. R., Brewer, S. H., and Phillips-Piro, C. M. (2021) Structural and spectrophotometric investigation of two unnatural amino-acid altered chromophores in the superfolder green fluorescent protein. Acta Crystallogr D Struct Biol. 77, 1010-1018
Nabel, K. G., Clark, S. A., Shankar, S., Pan, J., Clark, L. E., Yang, P., Coscia, A., McKay, L. G. A., Varnum, H. H., Brusic, V., Tolan, N. V., Zhou, G., Desjardins, M., Turbett, S. E., Kanjilal, S., Sherman, A. C., Dighe, A., LaRocque, R. C., Ryan, E. T., Tylek, C., Cohen-Solal, J. F., Darcy, A. T., Tavella, D., Clabbers, A., Fan, Y., Griffiths, A., Correia, I. R., Seagal, J., Baden, L. R., Charles, R. C., and Abraham, J. (2021) Structural basis for continued antibody evasion by the SARS-CoV-2 receptor binding domain. Science
Rechkoblit, O., Johnson, R. E., Gupta, Y. K., Prakash, L., Prakash, S., and Aggarwal, A. K. (2021) Structural basis of DNA synthesis opposite 8-oxoguanine by human PrimPol primase-polymerase. Nat Commun. 12, 4020
Kumar, S., Athreya, A., Gulati, A., Nair, R. Mony, Mahendran, I., Ranjan, R., and Penmatsa, A. (2021) Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol. 4, 836
Sander, C. L., Luu, J., Kim, K., Furkert, D., Jang, K., Reichenwallner, J., Kang, M. S., Lee, H. - J., Eger, B. T., Choe, H. - W., Fiedler, D., Ernst, O. P., Kim, Y. Ju, Palczewski, K., and Kiser, P. D. (2021) Structural evidence for visual arrestin priming via complexation of phosphoinositols. Structure. 10.1016/j.str.2021.10.002

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