Publications
(2017)
Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase. J Med Chem. 60, 1876-1891
(2017) First critical repressive H3K27me3 marks in embryonic stem cells identified using designed protein inhibitor. Proc Natl Acad Sci U S A. 10.1073/pnas.1706907114
(2017) The group II intron maturase: a reverse transcriptase and splicing factor go hand in hand. Curr Opin Struct Biol. 47, 30-39
(2017) Heme Oxygenase 2 Binds Myristate to Regulate Retrovirus Assembly and TLR4 Signaling. Cell Host Microbe. 21, 220-230
(2017) (2017) Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ.. Chem Res Toxicol. 10.1021/acs.chemrestox.7b00227
(2017) (2017) MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 10.7554/eLife.26693
(2017) MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 10.7554/eLife.26693
(2017) Molecular basis for the role of oncogenic histone mutations in modulating H3K36 methylation. Sci Rep. 7, 43906
(2017) (2017) (2017) Nickel Sequestration by the Host-Defense Protein Human Calprotectin. J Am Chem Soc. 10.1021/jacs.7b01212
(2017) NS3 from HCV strain JFH-1 is an unusually robust helicase that is primed to bind and unwind viral RNA. J Virol. 10.1128/JVI.01253-17
(2017) PAK4 crystal structures suggest unusual kinase conformational movements. Biochim Biophys Acta. 10.1016/j.bbapap.2017.10.004
(2017) Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca(2+)-dependent Cl(-) currents in human RPE. Elife. 10.7554/eLife.29914
(2017) The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis. Nature. 10.1038/nature23484
(2017) The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis. Nature. 10.1038/nature23484
(2017) The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis. Nature. 10.1038/nature23484
(2017) (2017) Recruitment of a SUMO isopeptidase to rDNA stabilizes silencing complexes by opposing SUMO targeted ubiquitin ligase activity. Genes Dev. 31, 802-815
(2017) Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.. Immunity. 46, 433-445
(2017) Small methyltransferase RlmH assembles a composite active site to methylate a ribosomal pseudouridine. Sci Rep. 7, 969
(2017) Staged induction of HIV-1 glycan-dependent broadly neutralizing antibodies. Sci Transl Med. 10.1126/scitranslmed.aai7514
(2017)