Publications
(2014)
Crystal structures of apparent saccharide sensors from histidine kinase receptors prevalent in a human gut symbiont. FEBS J. 281, 4263-79
(2014) Dimeric structure of pseudokinase RNase L bound to 2-5A reveals a basis for interferon-induced antiviral activity. Mol Cell. 53, 221-34
(2014) Dramatic improvement of crystals of large RNAs by cation replacement and dehydration. Structure. 22, 1363-71
(2014) E2 enzyme inhibition by stabilization of a low-affinity interface with ubiquitin. Nat Chem Biol. 10, 156-163
(2014) Ethenoguanines undergo glycosylation by nucleoside 2'-deoxyribosyltransferases at non-natural sites. PLoS One. 9, e115082
(2014) Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity. Mol Cell. 53, 140-7
(2014) Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly. Mol Cell. 56, 246-260
(2014) The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun. 5, 2987
(2014) The MHF complex senses branched DNA by binding a pair of crossover DNA duplexes. Nat Commun. 5, 2987
(2014) Molecular basis for disruption of E-cadherin adhesion by botulinum neurotoxin A complex. Science. 344, 1405-10
(2014) (2014) Molecular recognition and modification of the 30S ribosome by the aminoglycoside-resistance methyltransferase NpmA. Proc Natl Acad Sci U S A. 111, 6275-80
(2014) Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem. 57, 7016-30
(2014) (2014) (2014) (2014) (2014) Structural basis for the recruitment of glycogen synthase by glycogenin. Proc Natl Acad Sci U S A. 111, E2831-40
(2014) (2014) Structural basis of HIV-1 capsid recognition by PF74 and CPSF6. Proc Natl Acad Sci U S A. 111, 18625-30
(2014) Structural basis of the alternating-access mechanism in a bile acid transporter. Nature. 505, 569-73
(2014) Structural basis of the alternating-access mechanism in a bile acid transporter. Nature. 505, 569-73
(2014) (2014) (2014)