Publications

Found 1711 results
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2020
Reßing, N., Sönnichsen, M., Osko, J. D., Schöler, A., Schliehe-Diecks, J., Skerhut, A., Borkhardt, A., Hauer, J., Kassack, M. U., Christianson, D. W., Bhatia, S., and Hansen, F. K. (2020) Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups. J Med Chem. 63, 10339-10351
Reßing, N., Sönnichsen, M., Osko, J. D., Schöler, A., Schliehe-Diecks, J., Skerhut, A., Borkhardt, A., Hauer, J., Kassack, M. U., Christianson, D. W., Bhatia, S., and Hansen, F. K. (2020) Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping Groups. J Med Chem. 63, 10339-10351
Rohaim, A., Gong, L. D., Li, J., Rui, H., Blachowicz, L., and Roux, B. (2020) Open and Closed Structures of a Barium-Blocked Potassium Channel. J Mol Biol. 10.1016/j.jmb.2020.06.012
Mardirossian, M., Sola, R., Beckert, B., Valencic, E., Collis, D. W. P., Borišek, J., Armas, F., Di Stasi, A., Buchmann, J., Syroegin, E. A., Polikanov, Y., Magistrato, A., Hilpert, K., Wilson, D. N., and Scocchi, M. (2020) Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens. J Med Chem. 10.1021/acs.jmedchem.0c00665
Mardirossian, M., Sola, R., Beckert, B., Valencic, E., Collis, D. W. P., Borišek, J., Armas, F., Di Stasi, A., Buchmann, J., Syroegin, E. A., Polikanov, Y., Magistrato, A., Hilpert, K., Wilson, D. N., and Scocchi, M. (2020) Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens. J Med Chem. 10.1021/acs.jmedchem.0c00665
Mardirossian, M., Sola, R., Beckert, B., Valencic, E., Collis, D. W. P., Borišek, J., Armas, F., Di Stasi, A., Buchmann, J., Syroegin, E. A., Polikanov, Y., Magistrato, A., Hilpert, K., Wilson, D. N., and Scocchi, M. (2020) Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens. J Med Chem. 10.1021/acs.jmedchem.0c00665
Szewczyk, M. M., Ishikawa, Y., Organ, S., Sakai, N., Li, F., Halabelian, L., Ackloo, S., Couzens, A. L., Eram, M., Dilworth, D., Fukushi, H., Harding, R., Seña, C. C. Dela, Sugo, T., Hayashi, K., McLeod, D., Zepeda, C., Aman, A., Sánchez-Osuna, M., Bonneil, E., Takagi, S., Al-awar, R., Tyers, M., Richard, S., Takizawa, M., Gingras, A. - C., Arrowsmith, C. H., Vedadi, M., Brown, P. J., Nara, H., and Barsyte-Lovejoy, D. (2020) Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nat Commun. 11, 2396
Szewczyk, M. M., Ishikawa, Y., Organ, S., Sakai, N., Li, F., Halabelian, L., Ackloo, S., Couzens, A. L., Eram, M., Dilworth, D., Fukushi, H., Harding, R., Seña, C. C. Dela, Sugo, T., Hayashi, K., McLeod, D., Zepeda, C., Aman, A., Sánchez-Osuna, M., Bonneil, E., Takagi, S., Al-awar, R., Tyers, M., Richard, S., Takizawa, M., Gingras, A. - C., Arrowsmith, C. H., Vedadi, M., Brown, P. J., Nara, H., and Barsyte-Lovejoy, D. (2020) Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nat Commun. 11, 2396
Szewczyk, M. M., Ishikawa, Y., Organ, S., Sakai, N., Li, F., Halabelian, L., Ackloo, S., Couzens, A. L., Eram, M., Dilworth, D., Fukushi, H., Harding, R., Seña, C. C. Dela, Sugo, T., Hayashi, K., McLeod, D., Zepeda, C., Aman, A., Sánchez-Osuna, M., Bonneil, E., Takagi, S., Al-awar, R., Tyers, M., Richard, S., Takizawa, M., Gingras, A. - C., Arrowsmith, C. H., Vedadi, M., Brown, P. J., Nara, H., and Barsyte-Lovejoy, D. (2020) Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nat Commun. 11, 2396
Bertoletti, N., Chan, A. H., Schinazi, R. F., and Anderson, K. S. (2020) Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance. Molecules. 10.3390/molecules25204868
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Roark, R. S., Li, H., Williams, W. B., Chug, H., Mason, R. D., Gorman, J., Wang, S., Lee, F. - H., Rando, J., Bonsignori, M., Hwang, K. - K., Saunders, K. O., Wiehe, K., M Moody, A., Hraber, P. T., Wagh, K., Giorgi, E. E., Russell, R. M., Bibollet-Ruche, F., Liu, W., Connell, J., Smith, A. G., DeVoto, J., Murphy, A. I., Smith, J., Ding, W., Zhao, C., Chohan, N., Okumura, M., Rosario, C., Ding, Y., Lindemuth, E., Bauer, A. M., Bar, K. J., Ambrozak, D., Chao, C. W., Chuang, G. - Y., Geng, H., Lin, B. C., Louder, M. K., Nguyen, R., Zhang, B., Lewis, M. G., Raymond, D., Doria-Rose, N. A., Schramm, C. A., Douek, D. C., Roederer, M., Kepler, T. B., Kelsoe, G., Mascola, J. R., Kwong, P. D., Korber, B. T., Harrison, S. C., Haynes, B. F., Hahn, B. H., and Shaw, G. M. (2020) Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science. 10.1126/science.abd2638
Roark, R. S., Li, H., Williams, W. B., Chug, H., Mason, R. D., Gorman, J., Wang, S., Lee, F. - H., Rando, J., Bonsignori, M., Hwang, K. - K., Saunders, K. O., Wiehe, K., M Moody, A., Hraber, P. T., Wagh, K., Giorgi, E. E., Russell, R. M., Bibollet-Ruche, F., Liu, W., Connell, J., Smith, A. G., DeVoto, J., Murphy, A. I., Smith, J., Ding, W., Zhao, C., Chohan, N., Okumura, M., Rosario, C., Ding, Y., Lindemuth, E., Bauer, A. M., Bar, K. J., Ambrozak, D., Chao, C. W., Chuang, G. - Y., Geng, H., Lin, B. C., Louder, M. K., Nguyen, R., Zhang, B., Lewis, M. G., Raymond, D., Doria-Rose, N. A., Schramm, C. A., Douek, D. C., Roederer, M., Kepler, T. B., Kelsoe, G., Mascola, J. R., Kwong, P. D., Korber, B. T., Harrison, S. C., Haynes, B. F., Hahn, B. H., and Shaw, G. M. (2020) Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science. 10.1126/science.abd2638
Roark, R. S., Li, H., Williams, W. B., Chug, H., Mason, R. D., Gorman, J., Wang, S., Lee, F. - H., Rando, J., Bonsignori, M., Hwang, K. - K., Saunders, K. O., Wiehe, K., M Moody, A., Hraber, P. T., Wagh, K., Giorgi, E. E., Russell, R. M., Bibollet-Ruche, F., Liu, W., Connell, J., Smith, A. G., DeVoto, J., Murphy, A. I., Smith, J., Ding, W., Zhao, C., Chohan, N., Okumura, M., Rosario, C., Ding, Y., Lindemuth, E., Bauer, A. M., Bar, K. J., Ambrozak, D., Chao, C. W., Chuang, G. - Y., Geng, H., Lin, B. C., Louder, M. K., Nguyen, R., Zhang, B., Lewis, M. G., Raymond, D., Doria-Rose, N. A., Schramm, C. A., Douek, D. C., Roederer, M., Kepler, T. B., Kelsoe, G., Mascola, J. R., Kwong, P. D., Korber, B. T., Harrison, S. C., Haynes, B. F., Hahn, B. H., and Shaw, G. M. (2020) Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science. 10.1126/science.abd2638
Roark, R. S., Li, H., Williams, W. B., Chug, H., Mason, R. D., Gorman, J., Wang, S., Lee, F. - H., Rando, J., Bonsignori, M., Hwang, K. - K., Saunders, K. O., Wiehe, K., M Moody, A., Hraber, P. T., Wagh, K., Giorgi, E. E., Russell, R. M., Bibollet-Ruche, F., Liu, W., Connell, J., Smith, A. G., DeVoto, J., Murphy, A. I., Smith, J., Ding, W., Zhao, C., Chohan, N., Okumura, M., Rosario, C., Ding, Y., Lindemuth, E., Bauer, A. M., Bar, K. J., Ambrozak, D., Chao, C. W., Chuang, G. - Y., Geng, H., Lin, B. C., Louder, M. K., Nguyen, R., Zhang, B., Lewis, M. G., Raymond, D., Doria-Rose, N. A., Schramm, C. A., Douek, D. C., Roederer, M., Kepler, T. B., Kelsoe, G., Mascola, J. R., Kwong, P. D., Korber, B. T., Harrison, S. C., Haynes, B. F., Hahn, B. H., and Shaw, G. M. (2020) Recapitulation of HIV-1 Env-antibody coevolution in macaques leading to neutralization breadth. Science. 10.1126/science.abd2638
Chetty, A. K., Sexton, J. A., Ha, B. Hak, Turk, B. E., and Boggon, T. J. (2020) Recognition of physiological phosphorylation sites by p21-activated kinase 4. J Struct Biol. 211, 107553
Lee, S. - A., Yang, K. Jian Zhang, Brun, P. - J., Silvaroli, J. A., Yuen, J. J., Shmarakov, I., Jiang, H., Feranil, J. B., Li, X., Lackey, A. I., Krężel, W., Leibel, R. L., Libien, J., Storch, J., Golczak, M., and Blaner, W. S. (2020) Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv. 6, eaay8937
Lee, S. - A., Yang, K. Jian Zhang, Brun, P. - J., Silvaroli, J. A., Yuen, J. J., Shmarakov, I., Jiang, H., Feranil, J. B., Li, X., Lackey, A. I., Krężel, W., Leibel, R. L., Libien, J., Storch, J., Golczak, M., and Blaner, W. S. (2020) Retinol-binding protein 2 (RBP2) binds monoacylglycerols and modulates gut endocrine signaling and body weight. Sci Adv. 6, eaay8937

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