Publications

Found 1679 results
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2022
Mahoney, B. J., Takayesu, A., Zhou, A., Cascio, D., and Clubb, R. T. (2022) The structure of the Clostridium thermocellum RsgI9 ectodomain provides insight into the mechanism of biomass sensing. Proteins. 10.1002/prot.26326
Chen, B., Liu, Z., Perry, K., and Jin, R. (2022) Structure of the glucosyltransferase domain of TcdA in complex with RhoA provides insights into substrate recognition. Sci Rep. 12, 9028
Tararina, M. A., Yee, D. A., Tang, Y., and Christianson, D. W. (2022) Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C-N Bond-Forming Reaction of Flavunoidine Biosynthesis. Biochemistry. 10.1021/acs.biochem.2c00335
Cui, H., Divakaran, A., Hoell, Z. J., Ellingson, M. O., Scholtz, C. R., Zahid, H., Johnson, J. A., Griffith, E. C., Gee, C. T., Lee, A. L., Khanal, S., Shi, K., Aihara, H., Shah, V. H., Lee, R. E., Harki, D. A., and Pomerantz, W. C. K. (2022) A Structure-based Design Approach for Generating High Affinity BRD4 D1-Selective Chemical Probes. J Med Chem. 10.1021/acs.jmedchem.1c01779
Simon, B., Lou, H. Jane, Huet-Calderwood, C., Shi, G., Boggon, T. J., Turk, B. E., and Calderwood, D. A. (2022) Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry. Nat Commun. 13, 749
Lee, B. U., Papoutsis, B. M., Wong, N. Y., Piacentini, J., Kearney, C., Huggins, N. A., Cruz, N., Ng, T. T., Hao, K. Heather, Kramer, J. S., Fenlon, E. E., Nerenberg, P. S., Phillips-Piro, C. M., and Brewer, S. H. (2022) Unraveling Complex Local Protein Environments with 4-Cyano-l-phenylalanine. J Phys Chem B. 126, 8957-8969
Liu, C., Liu, H., Dasgupta, M., Hellman, L. M., Zhang, X., Qu, K., Xue, H., Wang, Y., Fan, F., Chang, Q., Yu, D., Ge, L., Zhang, Y., Cui, Z., Zhang, P., Heller, B., Zhang, H., Shi, B., Baker, B. M., and Liu, C. (2022) Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma. Sci Rep. 12, 12068
Liu, C., Liu, H., Dasgupta, M., Hellman, L. M., Zhang, X., Qu, K., Xue, H., Wang, Y., Fan, F., Chang, Q., Yu, D., Ge, L., Zhang, Y., Cui, Z., Zhang, P., Heller, B., Zhang, H., Shi, B., Baker, B. M., and Liu, C. (2022) Validation and promise of a TCR mimic antibody for cancer immunotherapy of hepatocellular carcinoma. Sci Rep. 12, 12068
2021
Cui, H., Carlson, A. S., Schleiff, M. A., Divakaran, A., Johnson, J. A., Buchholz, C. R., Zahid, H., Vail, N. R., Shi, K., Aihara, H., Harki, D. A., Miller, G. P., Topczewski, J. J., and Pomerantz, W. C. K. (2021) 4-Methyl-1,2,3-Triazoles as -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity. J Med Chem. 64, 10497-10511
Cui, H., Carlson, A. S., Schleiff, M. A., Divakaran, A., Johnson, J. A., Buchholz, C. R., Zahid, H., Vail, N. R., Shi, K., Aihara, H., Harki, D. A., Miller, G. P., Topczewski, J. J., and Pomerantz, W. C. K. (2021) 4-Methyl-1,2,3-Triazoles as -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity. J Med Chem. 64, 10497-10511
Pan, C., Zimmer, A., Shah, M., Huynh, M. Sang, Lai, C. Chieh- Lin, Sit, B., Hooda, Y., Curran, D. M., and Moraes, T. F. (2021) Actinobacillus utilizes a binding-protein dependent ABC transporter to acquire the active form of Vitamin B. J Biol Chem. 10.1016/j.jbc.2021.101046
Ferrero, S., Flores, M. D., Short, C., Vazquez, C. A., Clark, L. E., Ziegenbein, J., Zink, S., Fuentes, D., Payes, C., Batto, M. V., Collazo, M., García, C. C., Abraham, J., Cordo, S. M., Rodriguez, J. A., and Helguera, G. (2021) Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J Virol. 95, e0186820
Ferrero, S., Flores, M. D., Short, C., Vazquez, C. A., Clark, L. E., Ziegenbein, J., Zink, S., Fuentes, D., Payes, C., Batto, M. V., Collazo, M., García, C. C., Abraham, J., Cordo, S. M., Rodriguez, J. A., and Helguera, G. (2021) Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J Virol. 95, e0186820
Ferrero, S., Flores, M. D., Short, C., Vazquez, C. A., Clark, L. E., Ziegenbein, J., Zink, S., Fuentes, D., Payes, C., Batto, M. V., Collazo, M., García, C. C., Abraham, J., Cordo, S. M., Rodriguez, J. A., and Helguera, G. (2021) Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J Virol. 95, e0186820
Jobichen, C., Chong, T. Ying, Ling, T. Hui, and Sivaraman, J. (2021) The Autocatalytic Cleavage Domain Is Not Required for the Activity of ScpC, a Virulence Protease from : A Structural Insight. Biochemistry. 60, 1564-1568
Chen, C. - W., Pavlova, J. A., Lukianov, D. A., Tereshchenkov, A. G., Makarov, G. I., Khairullina, Z. Z., Tashlitsky, V. N., Paleskava, A., Konevega, A. L., Bogdanov, A. A., Osterman, I. A., Sumbatyan, N. V., and Polikanov, Y. S. (2021) Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics (Basel). 10.3390/antibiotics10040390
Kelso, S., Orlicky, S., Beenstock, J., Ceccarelli, D. F., Kurinov, I., Gish, G., and Sicheri, F. (2021) Bipartite binding of the N terminus of Skp2 to cyclin A. Structure. 10.1016/j.str.2021.04.011
Greaves, S. A., Ravindran, A., Santos, R. G., Chen, L., Falta, M. T., Wang, Y., Mitchell, A. M., Atif, S. M., Mack, D. G., Tinega, A. N., Maier, L. A., Dai, S., Pinilla, C., Grunewald, J., and Fontenot, A. P. (2021) CD4+ T cells in the lungs of acute sarcoidosis patients recognize an Aspergillus nidulans epitope. J Exp Med. 10.1084/jem.20210785
Slavik, K. M., Morehouse, B. R., Ragucci, A. E., Zhou, W., Ai, X., Chen, Y., Li, L., Wei, Z., Bähre, H., König, M., Seifert, R., S Y Lee, A., Cai, H., Imler, J. - L., and Kranzusch, P. J. (2021) cGAS-like receptors sense RNA and control 3'2'-cGAMP signaling in Drosophila. Nature. 10.1038/s41586-021-03743-5
Slavik, K. M., Morehouse, B. R., Ragucci, A. E., Zhou, W., Ai, X., Chen, Y., Li, L., Wei, Z., Bähre, H., König, M., Seifert, R., S Y Lee, A., Cai, H., Imler, J. - L., and Kranzusch, P. J. (2021) cGAS-like receptors sense RNA and control 3'2'-cGAMP signaling in Drosophila. Nature. 10.1038/s41586-021-03743-5
Liang, X., Qiu, X., Dionne, G., Cunningham, C. L., Pucak, M. L., Peng, G., Kim, Y. - H., Lauer, A., Shapiro, L., and Müller, U. (2021) CIB2 and CIB3 are auxiliary subunits of the mechanotransduction channel of hair cells. Neuron. 10.1016/j.neuron.2021.05.007
Hudson, J. D., Tamilselvan, E., Sotomayor, M., and Cooper, S. R. (2021) A complete Protocadherin-19 ectodomain model for evaluating epilepsy-causing mutations and potential protein interaction sites. Structure. 29, 1128-1143.e4
Bryan, C. M., Rocklin, G. J., Bick, M. J., Ford, A., Majri-Morrison, S., Kroll, A. V., Miller, C. J., Carter, L., Goreshnik, I., Kang, A., DiMaio, F., Tarbell, K. V., and Baker, D. (2021) Computational design of a synthetic PD-1 agonist. Proc Natl Acad Sci U S A. 10.1073/pnas.2102164118
Ippolito, J. A., Niu, H., Bertoletti, N., Carter, Z. J., Jin, S., Spasov, K. A., Cisneros, J. A., Valhondo, M., Cutrona, K. J., Anderson, K. S., and Jorgensen, W. L. (2021) Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. ACS Med Chem Lett. 12, 249-255
Ippolito, J. A., Niu, H., Bertoletti, N., Carter, Z. J., Jin, S., Spasov, K. A., Cisneros, J. A., Valhondo, M., Cutrona, K. J., Anderson, K. S., and Jorgensen, W. L. (2021) Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. ACS Med Chem Lett. 12, 249-255

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