Publications
(2025) Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.. Science. 389, 402-408
(2025) Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.. Science. 389, 402-408
(2025) Molecular glues that facilitate RAS binding to PI3Kα promote glucose uptake without insulin.. Science. 389, 402-408
(2025) A nut-and-bolt assembly of the bimodular large progenitor botulinum neurotoxin complex. Sci Adv. 11, eadx5831
(2025) Pharmacologic interrogation of USP28 cellular function in p53 signaling. Cell Chem Biol. 32, 1166-1182.e27
(2025) A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface. mBio. 16, e0089225
(2025) A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface. mBio. 16, e0089225
(2025) A protective and broadly binding antibody class engages the influenza virus hemagglutinin head at its stem interface. mBio. 16, e0089225
(2025) Spectroscopy and crystallography define carotenoid oxygenases as a new subclass of mononuclear non-heme Fe enzymes. J Biol Chem. 301, 108444
(2025) Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C. elegans development.. Nat Struct Mol Biol. 10.1038/s41594-025-01592-8
(2025) Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif. Structure. 10.1016/j.str.2025.11.003
(2025) Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350. Immunity. 58, 295-308.e5
(2025) Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350. Immunity. 58, 295-308.e5
(2025) The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors. Nat Commun. 10.1038/s41467-025-66967-3
(2025) Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3. Cell Rep. 10.1016/j.celrep.2025.116572
(2025) Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices. Nat Commun. 16, 8623
(2025) Structural insights into context-specific inhibition of bacterial translation by macrolides. Nat Commun. 16, 9685
(2025) Structure-guided discovery of viral proteins that inhibit host immunity. Cell. 10.1016/j.cell.2024.12.035
(2025) Structures of TGF-β with betaglycan and signaling receptors reveal mechanisms of complex assembly and signaling.. Nat Commun. 16, 1778
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112

