Publications
(2024) Novel Dihydropteridinone Derivatives As Potent Inhibitors of the Understudied Human Kinases Vaccinia-Related Kinase 1 and Casein Kinase 1δ/ε.. J Med Chem. 67, 8609-8629
(2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell. 187, 7214-7231.e23
(2024) Potent and broad HIV-1 neutralization in fusion peptide-primed SHIV-infected macaques. Cell. 187, 7214-7231.e23
(2024) A potential role for RNA aminoacylation prior to its role in peptide synthesis. Proc Natl Acad Sci U S A. 121, e2410206121
(2024) Preclinical proof of principle for orally delivered Th17 antagonist miniproteins. Cell. 187, 4305-4317.e18
(2024) Principles of paralog-specific targeted protein degradation engaging the C-degron E3 KLHDC2. Nat Commun. 15, 8829
(2024) Proof-of-concept studies with a computationally designed M inhibitor as a synergistic combination regimen alternative to Paxlovid. Proc Natl Acad Sci U S A. 121, e2320713121
(2024) An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc Natl Acad Sci U S A. 121, e2401136121
(2024) An RNA aptamer exploits exosite-dependent allostery to achieve specific inhibition of coagulation factor IXa. Proc Natl Acad Sci U S A. 121, e2401136121
(2024) Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun. 15, 5141
(2024) Simultaneous enhancement of multiple functional properties using evolution-informed protein design. Nat Commun. 15, 5141
(2024) Staphylococcus aureus skin colonization is mediated by SasG lectin variation. Cell Rep. 43, 114022
(2024) Structural basis for a highly conserved RNA-mediated enteroviral genome replication. Nucleic Acids Res. 10.1093/nar/gkae627
(2024) Structural basis for antibody recognition of the proximal MUC16 ectodomain. J Ovarian Res. 17, 41
(2024) Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases. Nat Commun. 15, 9899
(2024) Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases. Nat Commun. 15, 9899
(2024) Structural basis for promiscuity in ligand recognition by yjdF riboswitch. Cell Discov. 10, 37
(2024) Structural basis of Cfr-mediated antimicrobial resistance and mechanisms to evade it. Nat Chem Biol. 20, 867-876
(2024) Structural basis of divergent substrate recognition and inhibition of human neurolysin. Sci Rep. 14, 18420
(2024) Structural insights into the DNA-binding mechanism of BCL11A: The integral role of ZnF6. Structure. 32, 2276-2286.e4
(2024) Structural Insights into the DNA-Binding Mechanism of BCL11A: The Integral Role of ZnF6. bioRxiv. 10.1101/2024.01.17.576058
(2024) Structural requirements for activity of Mind bomb1 in Notch signaling. Structure. 32, 1667-1676.e5
(2024) Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding. Proc Natl Acad Sci U S A. 121, e2313677121

