Publications
(2025) Targeting N-Myc in neuroblastoma with selective Aurora kinase A degraders. Cell Chem Biol. 32, 352-362.e10
(2025) Targeting transcription factors through an IMiD independent zinc finger domain. EMBO Mol Med. 17, 1393-1416
(2025) Topobexin targets the Topoisomerase II ATPase domain for beta isoform-selective inhibition and anthracycline cardioprotection. Nat Commun. 16, 4928
(2025) Why Sulfur is Important in Lincosamide Antibiotics. Chem. 10.1016/j.chempr.2025.102480
(2026) Modelling of radiation damage and beam-induced heating of room-temperature samples at extremely high flux MX beamlines. IUCrJ. 10.1107/S2052252525011224
(2026) Serendipitous Discovery of an Allosteric Inhibitor Binding Groove in the Proline Biosynthetic Enzyme Pyrroline-5-Carboxylate Reductase 1 (PYCR1). Biochem J. 10.1042/BCJ20250278
(2026) Serendipitous Discovery of an Allosteric Inhibitor Binding Groove in the Proline Biosynthetic Enzyme Pyrroline-5-Carboxylate Reductase 1 (PYCR1). Biochem J. 10.1042/BCJ20250278
(2026) Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors. Nat Commun. 10.1038/s41467-026-68319-1

