Publications
(2025) Spectroscopy and crystallography define carotenoid oxygenases as a new subclass of mononuclear non-heme Fe enzymes. J Biol Chem. 301, 108444
(2025) Structural basis and functional roles for Toll-like receptor binding to Latrophilin in C. elegans development.. Nat Struct Mol Biol. 10.1038/s41594-025-01592-8
(2025) Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif. Structure. 10.1016/j.str.2025.11.003
(2025) Structural basis for complement receptor engagement and virus neutralization through Epstein-Barr virus gp350. Immunity. 58, 295-308.e5
(2025) Structural basis for LZTR1 recognition of RAS GTPases for degradation. Science. 389, 1112-1117
(2025) The structural basis for the selective antagonism of soluble TNF-alpha by shark variable new antigen receptors. Nat Commun. 10.1038/s41467-025-66967-3
(2025) Structural basis for varying drug resistance of SARS-CoV-2 M E166 variants. mBio. 16, e0262424
(2025) Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3. Cell Rep. 10.1016/j.celrep.2025.116572
(2025) Structural Impact of Ex Vivo Resistance Mutations on HIV-1 Integrase Polymers Induced by Allosteric Inhibitors. J Mol Biol. 437, 169224
(2025) Structural insights into chemoresistance mutants of BCL-2 and their targeting by stapled BAD BH3 helices. Nat Commun. 16, 8623
(2025) Structural insights into context-specific inhibition of bacterial translation by macrolides. Nat Commun. 16, 9685
(2025) Structural insights into context-specific inhibition of bacterial translation by macrolides. Nat Commun. 16, 9685
(2025) Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation.. Nat Commun. 16, 525
(2025) Structure-guided discovery of viral proteins that inhibit host immunity. Cell. 10.1016/j.cell.2024.12.035
(2025) Structure-guided discovery of viral proteins that inhibit host immunity. Cell. 10.1016/j.cell.2024.12.035
(2025) Structures of RNA phosphotransferase Tpt1 reveal distinct binding modes for an RNA 2'-PO splice junction versus a 5'-PO mononucleotide. RNA. 31, 916-922
(2025) Synthetic antibodies targeting EphA2 induce diverse signaling-competent clusters with differential activation. Protein Sci. 34, e70145
(2025) Synthetic antibodies targeting EphA2 induce diverse signaling-competent clusters with differential activation. Protein Sci. 34, e70145
(2025) Synthetic antibodies targeting EphA2 induce diverse signaling-competent clusters with differential activation. Protein Sci. 34, e70145
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112
(2025) A Target Class Ligandability Evaluation of WD40 Repeat-Containing Proteins. J Med Chem. 68, 1092-1112

