Publications

Found 9 results
Filters: Author is Laganowsky, Arthur  [Clear All Filters]
2010
Laganowsky, A., Benesch, J. L. P., Landau, M., Ding, L., Sawaya, M. R., Cascio, D., Huang, Q., Robinson, C. V., Horwitz, J., and Eisenberg, D. (2010) Crystal structures of truncated alphaA and alphaB crystallins reveal structural mechanisms of polydispersity important for eye lens function. Protein Sci. 19, 1031-43
2011
Laganowsky, A., Zhao, M., Soriaga, A. B., Sawaya, M. R., Cascio, D., and Yeates, T. O. (2011) An approach to crystallizing proteins by metal-mediated synthetic symmetrization. Protein Sci. 20, 1876-90
Colletier, J. - P., Laganowsky, A., Landau, M., Zhao, M., Soriaga, A. B., Goldschmidt, L., Flot, D., Cascio, D., Sawaya, M. R., and Eisenberg, D. (2011) Molecular basis for amyloid-beta polymorphism. Proc Natl Acad Sci U S A. 108, 16938-43
Landau, M., Sawaya, M. R., Faull, K. F., Laganowsky, A., Jiang, L., Sievers, S. A., Liu, J., Barrio, J. R., and Eisenberg, D. (2011) Towards a pharmacophore for amyloid. PLoS Biol. 9, e1001080
2012
Laganowsky, A., Liu, C., Sawaya, M. R., Whitelegge, J. P., Park, J., Zhao, M., Pensalfini, A., Soriaga, A. B., Landau, M., Teng, P. K., Cascio, D., Glabe, C., and Eisenberg, D. (2012) Atomic view of a toxic amyloid small oligomer. Science. 335, 1228-31
2014
Lai, Y. - T., Reading, E., Hura, G. L., Tsai, K. - L., Laganowsky, A., Asturias, F. J., Tainer, J. A., Robinson, C. V., and Yeates, T. O. (2014) Structure of a designed protein cage that self-assembles into a highly porous cube. Nat Chem. 6, 1065-71
Hochberg, G. K. A., Ecroyd, H., Liu, C., Cox, D., Cascio, D., Sawaya, M. R., Collier, M. P., Stroud, J., Carver, J. A., Baldwin, A. J., Robinson, C. V., Eisenberg, D. S., Benesch, J. L. P., and Laganowsky, A. (2014) The structured core domain of αB-crystallin can prevent amyloid fibrillation and associated toxicity.. Proc Natl Acad Sci U S A. 111, E1562-70
2018
Patrick, J. W., Boone, C. D., Liu, W., Conover, G. M., Liu, Y., Cong, X., and Laganowsky, A. (2018) Allostery revealed within lipid binding events to membrane proteins. Proc Natl Acad Sci U S A. 115, 2976-2981
2022
Lyu, J., Liu, C., Zhang, T., Schrecke, S., Elam, N. P., Packianathan, C., Hochberg, G. K. A., Russell, D., Zhao, M., and Laganowsky, A. (2022) Structural basis for lipid and copper regulation of the ABC transporter MsbA. Nat Commun. 13, 7291