Publications

Found 3 results
Filters: Author is Secrist, John A  [Clear All Filters]
2006
Zhang, Y., Secrist, J. A., and Ealick, S. E. (2006) The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation. Acta Crystallogr D Biol Crystallogr. 62, 133-9
2009
McCloskey, D. E., Bale, S., Secrist, J. A., Tiwari, A., Moss, T. H., Valiyaveettil, J., Brooks, W. H., Guida, W. C., Pegg, A. E., and Ealick, S. E. (2009) New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine. J Med Chem. 52, 1388-407
2011
Seckute, J., McCloskey, D. E., H Thomas, J., Secrist, J. A., Pegg, A. E., and Ealick, S. E. (2011) Binding and inhibition of human spermidine synthase by decarboxylated S-adenosylhomocysteine. Protein Sci. 20, 1836-44