Publications
(2023)
Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY. Nat Commun. 14, 597
(2023) Engineered Antigen-Binding Fragments for Enhanced Crystallization of Antibody:Antigen Complexes. Protein Sci. 10.1002/pro.4824
(2023) Epstein-Barr Virus Encoded BCL2, BHRF1, Downregulates Autophagy by Noncanonical Binding of BECN1. Biochemistry. 62, 2934-2951
(2023) An examination of the metal ion content in the active sites of human endonucleases CPSF73 and INTS11. J Biol Chem. 299, 103047
(2023) (2023) (2022) (2022)
Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels. J Gen Physiol. 10.1085/jgp.202112965
(2022) Epstein-Barr virus gH/gL has multiple sites of vulnerability for virus neutralization and fusion inhibition. Immunity. 55, 2135-2148.e6
(2022) Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants. Emerg Microbes Infect. 11, 548-551
(2022) Exploration of Structured Symmetric Cyclic Peptides as Ligands for Metal-Organic Frameworks. Chem Mater. 34, 9736-9744
(2022) (2022) Effector-mediated membrane disruption controls cell death in CBASS antiphage defense. Mol Cell. 10.1016/j.molcel.2021.10.020
(2021) Efficacy of epetraborole against Mycobacterium abscessus is increased with norvaline. PLoS Pathog. 17, e1009965
(2021) Elucidation of Diverse Solid-State Packing in a Family of Electron-Deficient Expanded Helicenes via Microcrystal Electron Diffraction (MicroED)*. Angew Chem Int Ed Engl. 60, 2493-2499
(2021) Engineering the Prenyltransferase Domain of a Bifunctional Assembly-Line Terpene Synthase. Biochemistry. 60, 3162-3172
(2021) The Ephb2 Receptor Uses Homotypic, Head-to-Tail Interactions within Its Ectodomain as an Autoinhibitory Control Mechanism. Int J Mol Sci. 10.3390/ijms221910473
(2021) (2021) Exploring Ligand-Directed -Acyl--alkylsulfonamide-Based Acylation Chemistry for Potential Targeted Degrader Development. ACS Med Chem Lett. 12, 1302-1307
(2021) The Effects of Framework Mutations at the Variable Domain Interface on Antibody Affinity Maturation in an HIV-1 Broadly Neutralizing Antibody Lineage. Front Immunol. 11, 1529
(2020) Exploring Structural Determinants of Inhibitor Affinity and Selectivity in Complexes with Histone Deacetylase 6. J Med Chem. 63, 295-308
(2020) Extensive dissemination and intraclonal maturation of HIV Env vaccine-induced B cell responses. J Exp Med. 10.1084/jem.20191155
(2020) Enhancing subtilisin thermostability through a modified normalized B-factor analysis and loop-grafting strategy. J Biol Chem. 10.1074/jbc.RA119.010658
(2019) An ensemble of lipoxygenase structures reveals novel conformations of the Fe coordination sphere. Protein Sci. 10.1002/pro.3602
(2019)