Found 91 results
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Tran, B., Pichling, P., Tenney, L., Connelly, C. M., Moon, M. H., Ferré-D'Amaré, A. R., Schneekloth, J. S., and Jones, C. P. (2020) Parallel Discovery Strategies Provide a Basis for Riboswitch Ligand Design. Cell Chem Biol. 10.1016/j.chembiol.2020.07.021
Mardirossian, M., Sola, R., Beckert, B., Valencic, E., Collis, D. W. P., Borišek, J., Armas, F., Di Stasi, A., Buchmann, J., Syroegin, E. A., Polikanov, Y., Magistrato, A., Hilpert, K., Wilson, D. N., and Scocchi, M. (2020) Peptide inhibitors of bacterial protein synthesis with broad spectrum and SbmA-independent bactericidal activity against clinical pathogens. J Med Chem. 10.1021/acs.jmedchem.0c00665
Szewczyk, M. M., Ishikawa, Y., Organ, S., Sakai, N., Li, F., Halabelian, L., Ackloo, S., Couzens, A. L., Eram, M., Dilworth, D., Fukushi, H., Harding, R., Seña, C. C. Dela, Sugo, T., Hayashi, K., McLeod, D., Zepeda, C., Aman, A., Sánchez-Osuna, M., Bonneil, E., Takagi, S., Al-awar, R., Tyers, M., Richard, S., Takizawa, M., Gingras, A. - C., Arrowsmith, C. H., Vedadi, M., Brown, P. J., Nara, H., and Barsyte-Lovejoy, D. (2020) Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nat Commun. 11, 2396
Stoddard, P. R., Lynch, E. M., Farrell, D. P., Dosey, A. M., DiMaio, F., Williams, T. A., Kollman, J. M., Murray, A. W., and Garner, E. C. (2020) Polymerization in the actin ATPase clan regulates hexokinase activity in yeast. Science. 367, 1039-1042
Bertoletti, N., Chan, A. H., Schinazi, R. F., and Anderson, K. S. (2020) Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance. Molecules. 10.3390/molecules25204868
Dussupt, V., Sankhala, R. S., Gromowski, G. D., Donofrio, G., De La Barrera, R. A., Larocca, R. A., Zaky, W., Mendez-Rivera, L., Choe, M., Davidson, E., McCracken, M. K., Brien, J. D., Abbink, P., Bai, H., Bryan, A. L., Bias, C. Hope, Berry, I. Maljkovic, Botero, N., Cook, T., Doria-Rose, N. A., Escuer, A. Grinyo I., Frimpong, J. Akuoku, Geretz, A., Hernandez, M., Hollidge, B. S., Jian, N., Kabra, K., Leggat, D. J., Liu, J., Pinto, A. K., Rutvisuttinunt, W., Setliff, I., Tran, U., Townsley, S., Doranz, B. J., Rolland, M., McDermott, A. B., Georgiev, I. S., Thomas, R., Robb, M. L., Eckels, K. H., Barranco, E., Koren, M., Smith, D. R., Jarman, R. G., George, S. L., Stephenson, K. E., Barouch, D. H., Modjarrad, K., Michael, N. L., M Joyce, G., and Krebs, S. J. (2020) Potent Zika and dengue cross-neutralizing antibodies induced by Zika vaccination in a dengue-experienced donor. Nat Med. 26, 228-235
Wang, B., Grant, R. A., and Laub, M. T. (2020) ppGpp Coordinates Nucleotide and Amino-Acid Synthesis in E. coli During Starvation.. Mol Cell. 10.1016/j.molcel.2020.08.005
Peterson, B. N., Young, M. K. M., Luo, S., Wang, J., Whiteley, A. T., Woodward, J. J., Tong, L., Wang, J. D., and Portnoy, D. A. (2020) (p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes. mBio. 10.1128/mBio.01625-20
Gao, A., Vasilyev, N., Kaushik, A., Duan, W., and Serganov, A. (2020) Principles of RNA and nucleotide discrimination by the RNA processing enzyme RppH. Nucleic Acids Res. 10.1093/nar/gkaa024
Jenson, J. M., Xue, V., Stretz, L., Mandal, T., Reich, L. Luther, and Keating, A. E. (2018) Peptide design by optimization on a data-parameterized protein interaction landscape. Proc Natl Acad Sci U S A. 115, E10342-E10351
Hand, T. H., Das, A., Roth, M. O., Smith, C. L., Jean-Baptiste, U. L., and Li, H. (2018) Phosphate Lock Residues of Acidothermus cellulolyticus Cas9 Are Critical to Its Substrate Specificity. ACS Synth Biol. 7, 2908-2917
Alex, J. M., Rennie, M. L., Volpi, S., Sansone, F., Casnati, A., and Crowley, P. B. (2018) Phosphonated Calixarene as a "€œMolecular Glue"€ for Protein Crystallization. Crystal Growth & DesignCryst. Growth Des. 18, 2467-2473
Hammill, J. T., Scott, D. C., Min, J., Connelly, M. C., Holbrook, G., Zhu, F., Matheny, A., Yang, L., Singh, B., Schulman, B. A., and R Guy, K. (2018) Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. J Med Chem. 61, 2680-2693
Nowak, R. P., DeAngelo, S. L., Buckley, D., He, Z., Donovan, K. A., An, J., Safaee, N., Jedrychowski, M. P., Ponthier, C. M., Ishoey, M., Zhang, T., Mancias, J. D., Gray, N. S., Bradner, J. E., and Fischer, E. S. (2018) Plasticity in binding confers selectivity in ligand-induced protein degradation. Nat Chem Biol. 10.1038/s41589-018-0055-y
Qi, J., Li, X., Peng, H., Cook, E. M., Dadashian, E. L., Wiestner, A., Park, H. J., and Rader, C. (2018) Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1. Proc Natl Acad Sci U S A. 115, E5467-E5476
Sui, X., Farquhar, E. R., Hill, H. E., von Lintig, J., Shi, W., and Kiser, P. D. (2018) Preparation and characterization of metal-substituted carotenoid cleavage oxygenases. J Biol Inorg Chem. 23, 887-901
Novikova, I. V., Sharma, N., Moser, T., Sontag, R., Liu, Y., Collazo, M. J., Cascio, D., Shokuhfar, T., Hellmann, H., Knoblauch, M., and Evans, J. E. (2018) Protein structural biology using cell-free platform from wheat germ. Adv Struct Chem Imaging. 4, 13