Publications

Found 818 results
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2015
Zhang, J., Kiser, P. D., Badiee, M., Palczewska, G., Dong, Z., Golczak, M., Tochtrop, G. P., and Palczewski, K. (2015) Molecular pharmacodynamics of emixustat in protection against retinal degeneration. J Clin Invest. 125, 2781-94
Noey, E. L., Tibrewal, N., Jiménez-Osés, G., Osuna, S., Park, J., Bond, C. M., Cascio, D., Liang, J., Zhang, X., Huisman, G. W., Tang, Y., and Houk, K. N. (2015) Origins of stereoselectivity in evolved ketoreductases. Proc Natl Acad Sci U S A. 112, E7065-72
Noey, E. L., Tibrewal, N., Jiménez-Osés, G., Osuna, S., Park, J., Bond, C. M., Cascio, D., Liang, J., Zhang, X., Huisman, G. W., Tang, Y., and Houk, K. N. (2015) Origins of stereoselectivity in evolved ketoreductases. Proc Natl Acad Sci U S A. 112, E7065-72
Yudina, Z., Roa, A., Johnson, R., Biris, N., Vieira, D. A. de Souza, Tsiperson, V., Reszka, N., Taylor, A. B., P Hart, J., Demeler, B., Diaz-Griffero, F., and Ivanov, D. N. (2015) RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.. Cell Rep. 12, 788-97
Yudina, Z., Roa, A., Johnson, R., Biris, N., Vieira, D. A. de Souza, Tsiperson, V., Reszka, N., Taylor, A. B., P Hart, J., Demeler, B., Diaz-Griffero, F., and Ivanov, D. N. (2015) RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.. Cell Rep. 12, 788-97
Taylor, A. B., Pica-Mattoccia, L., Polcaro, C. M., Donati, E., Cao, X., Basso, A., Guidi, A., Rugel, A. R., Holloway, S. P., Anderson, T. J. C., P Hart, J., Cioli, D., and LoVerde, P. T. (2015) Structural and Functional Characterization of the Enantiomers of the Antischistosomal Drug Oxamniquine. PLoS Negl Trop Dis. 9, e0004132
Clarke, O. B., Tomasek, D., Jorge, C. D., Dufrisne, M. Belcher, Kim, M., Banerjee, S., Rajashankar, K. R., Shapiro, L., Hendrickson, W. A., Santos, H., and Mancia, F. (2015) Structural basis for phosphatidylinositol-phosphate biosynthesis. Nat Commun. 6, 8505
Dong, C., Mao, Y., Tempel, W., Qin, S., Li, L., Loppnau, P., Huang, R., and Min, J. (2015) Structural basis for substrate recognition by the human N-terminal methyltransferase 1. Genes Dev. 29, 2343-8
Luo, M., and Tanner, J. J. (2015) Structural Basis of Substrate Recognition by Aldehyde Dehydrogenase 7A1. Biochemistry. 54, 5513-22
Fisher, O. S., Deng, H., Liu, D., Zhang, Y., Wei, R., Deng, Y., Zhang, F., Louvi, A., Turk, B. E., Boggon, T. J., and Su, B. (2015) Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex. Nat Commun. 6, 7937
Tao, Y., Cheung, L. S., Li, S., Eom, J. - S., Chen, L. - Q., Xu, Y., Perry, K., Frommer, W. B., and Feng, L. (2015) Structure of a eukaryotic SWEET transporter in a homotrimeric complex. Nature. 527, 259-263
Mi, L. - Z., Brown, C. T., Gao, Y., Tian, Y., Le, V. Q., Walz, T., and Springer, T. A. (2015) Structure of bone morphogenetic protein 9 procomplex. Proc Natl Acad Sci U S A. 112, 3710-5
Becker, A., Kannan, T. R., Taylor, A. B., Pakhomova, O. N., Zhang, Y., Somarajan, S. R., Galaleldeen, A., Holloway, S. P., Baseman, J. B., and P Hart, J. (2015) Structure of CARDS toxin, a unique ADP-ribosylating and vacuolating cytotoxin from Mycoplasma pneumoniae. Proc Natl Acad Sci U S A. 112, 5165-70
D'Antonio, E. L., Deinema, M. S., Kearns, S. P., Frey, T. A., Tanghe, S., Perry, K., Roy, T. A., Gracz, H. S., Rodriguez, A., and D'Antonio, J. (2015) Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase. Mol Biochem Parasitol. 204, 64-76
Lall, P., Lindsay, A. J., Hanscom, S., Kecman, T., Taglauer, E. S., McVeigh, U. M., Franklin, E., McCaffrey, M. W., and Khan, A. R. (2015) Structure-Function Analyses of the Interactions between Rab11 and Rab14 Small GTPases with Their Shared Effector Rab Coupling Protein (RCP). J Biol Chem. 290, 18817-32
McNamara, D. E., Senese, S., Yeates, T. O., and Torres, J. Z. (2015) Structures of potent anticancer compounds bound to tubulin. Protein Sci. 24, 1164-72
Leibly, D. J., Arbing, M. A., Pashkov, I., DeVore, N., Waldo, G. S., Terwilliger, T. C., and Yeates, T. O. (2015) A Suite of Engineered GFP Molecules for Oligomeric Scaffolding. Structure. 23, 1754-1768
Schmidt, A. G., Therkelsen, M. D., Stewart, S., Kepler, T. B., Liao, H. - X., M Moody, A., Haynes, B. F., and Harrison, S. C. (2015) Viral receptor-binding site antibodies with diverse germline origins. Cell. 161, 1026-1034
2014
Polikanov, Y. S., Osterman, I. A., Szal, T., Tashlitsky, V. N., Serebryakova, M. V., Kusochek, P., Bulkley, D., Malanicheva, I. A., Efimenko, T. A., Efremenkova, O. V., Konevega, A. L., Shaw, K. J., Bogdanov, A. A., Rodnina, M. V., Dontsova, O. A., Mankin, A. S., Steitz, T. A., and Sergiev, P. V. (2014) Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol Cell. 56, 531-40
Gao, P., Zillinger, T., Wang, W., Ascano, M., Dai, P., Hartmann, G., Tuschl, T., Deng, L., Barchet, W., and Patel, D. J. (2014) Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA. Cell Rep. 8, 1668-1676
Gleason, J. E., Galaleldeen, A., Peterson, R. L., Taylor, A. B., Holloway, S. P., Waninger-Saroni, J., Cormack, B. P., Cabelli, D. E., P Hart, J., and Culotta, V. Cizewski (2014) Candida albicans SOD5 represents the prototype of an unprecedented class of Cu-only superoxide dismutases required for pathogen defense. Proc Natl Acad Sci U S A. 111, 5866-71
Spicer, T. P., Jiang, J., Taylor, A. B., Choi, J. Yong, P Hart, J., Roush, W. R., Fields, G. B., Hodder, P. S., and Minond, D. (2014) Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. J Med Chem. 57, 9598-611
Liu, D. S., Nivón, L. G., Richter, F., Goldman, P. J., Deerinck, T. J., Yao, J. Z., Richardson, D., Phipps, W. S., Ye, A. Z., Ellisman, M. H., Drennan, C. L., Baker, D., and Ting, A. Y. (2014) Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc Natl Acad Sci U S A. 111, E4551-9
Da Fonseca, I., Qureshi, I. A., Mehra-Chaudhary, R., Kizjakina, K., Tanner, J. J., and Sobrado, P. (2014) Contributions of unique active site residues of eukaryotic UDP-galactopyranose mutases to substrate recognition and active site dynamics. Biochemistry. 53, 7794-804
Cavalier, M. C., Pierce, A. D., Wilder, P. T., Alasady, M. J., Hartman, K. G., Neau, D. B., Foley, T. L., Jadhav, A., Maloney, D. J., Simeonov, A., Toth, E. A., and Weber, D. J. (2014) Covalent small molecule inhibitors of Ca(2+)-bound S100B. Biochemistry. 53, 6628-40

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