Publications
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(2018)
Patient-specific mutations impair BESTROPHIN1's essential role in mediating Ca(2+)-dependent Cl(-) currents in human RPE. Elife. 10.7554/eLife.29914
(2017) (2016) Structural insights into the promiscuous DNA binding and broad substrate selectivity of fowlpox virus resolvase. Sci Rep. 10, 393
(2020) Structural analysis and optimization of the covalent association between SpyCatcher and a peptide Tag. J Mol Biol. 426, 309-17
(2014) 3.3 Å structure of Niemann-Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport.. Proc Natl Acad Sci U S A. 114, 9116-9121
(2017) Norathyriol suppresses skin cancers induced by solar ultraviolet radiation by targeting ERK kinases. Cancer Res. 72, 260-70
(2012) (2023) (2021) (2023) cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell. 186, 3261-3276.e20
(2023) (2021) Molecular basis for site-specific read-out of histone H3K4me3 by the BPTF PHD finger of NURF. Nature. 442, 91-5
(2006) Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. EMBO J. 10.15252/embj.2021108368
(2022) ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. J Med Chem. 67, 2837-2848
(2024) (2010) Structural basis for small G protein effector interaction of Ras-related protein 1 (Rap1) and adaptor protein Krev interaction trapped 1 (KRIT1). J Biol Chem. 287, 22317-27
(2012) Cystine-knot peptide inhibitors of HTRA1 bind to a cryptic pocket within the active site region. Nat Commun. 15, 4359
(2024) Fjord-Edge Graphene Nanoribbons with Site-Specific Nitrogen Substitution. J Am Chem Soc. 142, 18093-18102
(2020) The structure of fly Teneurin-m reveals an asymmetric self-assembly that allows expansion into zippers. EMBO Rep. 10.15252/embr.202256728
(2023) (2024) (2016) Structural basis for multifunctional roles of human Ints3 C-terminal domain. J Biol Chem. 10.1074/jbc.RA120.016393
(2020) Balanced interactions of calcineurin with AKAP79 regulate Ca2+-calcineurin-NFAT signaling. Nat Struct Mol Biol. 19, 337-45
(2012) (2021)