Publications
Atomic structures of the RNA end-healing 5'-OH kinase and 2',3'-cyclic phosphodiesterase domains of fungal tRNA ligase: conformational switches in the kinase upon binding of the GTP phosphate donor. Nucleic Acids Res. 10.1093/nar/gkz1049
(2019) (2014) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Biophysical Society 62nd Annual Meeting, Feb 17-21, 2018
(2018) Challenging Structural Biology Research at NE-CAT. BES Trienniel Review of the APS, August 15, 2017
(2017) Structure of 3'-PO/5'-OH RNA ligase RtcB in complex with a 5'-OH oligonucleotide. RNA. 10.1261/rna.078692.121
(2021) The Critical Tools Needed To Deal with Challenging Structural Biology Projects. Chemistry Colloquium, Shiv Nadar University
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2016 Annual Meeting of the American Crystallographic Association, July 22-26, 2016
(2016) Structural Biology in Drug Discovery. Calcutta University
(2021) Determination of the X-ray structure of the snake venom protein omwaprin by total chemical synthesis and racemic protein crystallography. Protein Sci. 19, 1840-9
(2010) Crystal structure of the human Polϵ B-subunit in complex with the C-terminal domain of the catalytic subunit.. J Biol Chem. 10.1074/jbc.M117.792705
(2017) Crystallization and preliminary X-ray diffraction analysis of human DNA primase. Acta Crystallogr F Struct Biol Commun. 70, 206-10
(2014) (2014) (2016) (2015) Activity and fidelity of human DNA polymerase α depend on primer structure.. J Biol Chem. 10.1074/jbc.RA117.001074
(2018) Structural and functional insight into mismatch extension by human DNA polymerase α.. Proc Natl Acad Sci U S A. 119, e2111744119
(2022) Discovery of Peptidomimetic Ligands of EED as Allosteric Inhibitors of PRC2. ACS Comb Sci. 19, 161-172
(2017) Structure and axon outgrowth inhibitor binding of the Nogo-66 receptor and related proteins. EMBO J. 22, 3291-302
(2003) Crystal structures of the Tie2 receptor ectodomain and the angiopoietin-2-Tie2 complex. Nat Struct Mol Biol. 13, 524-32
(2006) Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel. Elife. 10.7554/eLife.23886
(2017) Mechanically rigid supramolecular assemblies formed from an Fmoc-guanine conjugated peptide nucleic acid. Nat Commun. 10, 5256
(2019) The leukodystrophy protein FAM126A (hyccin) regulates PtdIns(4)P synthesis at the plasma membrane.. Nat Cell Biol. 18, 132-8
(2016) Tuning the Metabolic Stability of Visual Cycle Modulators through Modification of an RPE65 Recognition Motif. J Med Chem. 66, 8140-8158
(2023) Structure of telomerase protein Pof8 C-terminal domain is an xRRM conserved among LARP7 proteins. RNA Biol. 10.1080/15476286.2020.1836891
(2020) The nascent RNA binding complex SFiNX licenses piRNA-guided heterochromatin formation. Nat Struct Mol Biol. 26, 720-731
(2019)