Publications
(2020)
Structure of the Receptor Binding Domain of EnvP(b)1, an Endogenous Retroviral Envelope Protein Expressed in Human Tissues. mBio. 10.1128/mBio.02772-20
(2020) Structure of the Regulatory Cytosolic Domain of a Eukaryotic Potassium-Chloride Cotransporter. Structure. 10.1016/j.str.2020.06.009
(2020) "The structure of the Type III secretion system export gate with CdsO, an ATPase lever arm". PLoS Pathog. 16, e1008923
(2020) Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. ACS Med Chem Lett. 11, 346-352
(2020) Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proc Natl Acad Sci U S A. 10.1073/pnas.2018156117
(2020) Structure-function analysis of microRNA 3'-end trimming by Nibbler. Proc Natl Acad Sci U S A. 10.1073/pnas.2018156117
(2020) Structure-function insights into the initial step of DNA integration by a CRISPR-Cas-Transposon complex. Cell Res. 10.1038/s41422-019-0272-2
(2020) Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair. Structure. 10.1016/j.str.2020.04.007
(2020) Structures of diverse poxin cGAMP nucleases reveal a widespread role for cGAS-STING evasion in host-pathogen conflict. Elife. 10.7554/eLife.59753
(2020) Symmetry Breaking and Structural Polymorphism in a Bacterial Microcompartment Shell Protein for Choline Utilization. Protein Sci. 10.1002/pro.3941
(2020) (2020) (2020) Second Messenger cA Formation within the Composite Csm1 Palm Pocket of Type III-A CRISPR-Cas Csm Complex and Its Release Path. Mol Cell. 75, 933-943.e6
(2019) Selective inactivation of hypomethylating agents by SAMHD1 provides a rationale for therapeutic stratification in AML. Nat Commun. 10, 3475
(2019) Serotonin transporter-ibogaine complexes illuminate mechanisms of inhibition and transport. Nature. 569, 141-145
(2019) (2019) Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia. Nat Commun. 10, 2691
(2019) Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants. J Mol Biol. 431, 576-592
(2019) Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from . Biochemistry. 58, 5011-5021
(2019) Structural and functional analyses reveal promiscuous and species specific use of ephrin receptors by Cedar virus. Proc Natl Acad Sci U S A. 116, 20707-20715
(2019) Structural and Functional Analysis of Ubiquitin-based inhibitors that Target the Backsides of E2 Enzymes. J Mol Biol. 10.1016/j.jmb.2019.09.024
(2019) Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure. 27, 590-605.e5
(2019) (2019) Structural and functional evidence that lipoprotein LpqN supports cell envelope biogenesis in . J Biol Chem. 10.1074/jbc.RA119.008781
(2019)