Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC.

Publication Type:

Journal Article

Authors:

Gero, Thomas W; Heppner, David E; Beyett, Tyler S; To, Ciric; Azevedo, Seth C; Jang, Jaebong; Bunnell, Thomas; Feru, Frederic; Li, Zhengnian; Hee Shin, Bo; Soroko, Kara M; Gokhale, Prafulla C; Gray, Nathanael S; Jänne, Pasi A; Eck, Michael J; Scott, David A

Source:

Bioorg Med Chem Lett, p.128718 (2022)
PDB: 
7LTX
Detector: 
EIGER
Beamline: 
24-ID-C