Publications

Found 1264 results
Filters: First Letter Of Last Name is H  [Clear All Filters]
2022
Hong, Z., Adlakha, J., Wan, N., Guinn, E., Giska, F., Gupta, K., Melia, T. J., and Reinisch, K. M. (2022) Mitoguardin-2-mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation. J Cell Biol. 10.1083/jcb.202207022
Beyett, T. S., To, C., Heppner, D. E., Rana, J. K., Schmoker, A. M., Jang, J., De Clercq, D. J. H., Gomez, G., Scott, D. A., Gray, N. S., Jänne, P. A., and Eck, M. J. (2022) Molecular basis for cooperative binding and synergy of ATP-site and allosteric EGFR inhibitors. Nat Commun. 13, 2530
Ha, B. Hak, Yigit, S., Natarajan, N., Morse, E. M., Calderwood, D. A., and Boggon, T. J. (2022) Molecular basis for integrin adhesion receptor binding to p21-activated kinase 4 (PAK4). Commun Biol. 5, 1257
Hwang, T., Parker, S. S., Hill, S. M., Grant, R. A., Ilunga, M. W., Sivaraman, V., Mouneimne, G., and Keating, A. E. (2022) Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH. Elife. 10.7554/eLife.70680
Hwang, T., Parker, S. S., Hill, S. M., Grant, R. A., Ilunga, M. W., Sivaraman, V., Mouneimne, G., and Keating, A. E. (2022) Native proline-rich motifs exploit sequence context to target actin-remodeling Ena/VASP protein ENAH. Elife. 10.7554/eLife.70680
Greisman, J. B., Dalton, K. M., Sheehan, C. J., Klureza, M. A., Kurinov, I., and Hekstra, D. R. (2022) Native SAD phasing at room temperature. Acta Crystallogr D Struct Biol. 78, 986-996
Son, J., Jang, J., Beyett, T. S., Eum, Y., Haikala, H. M., Verano, A., Lin, M., Hatcher, J. M., Kwiatkowski, N. P., Eser, P. Özden, Poitras, M. J., Wang, S., Xu, M., Gokhale, P. C., Cameron, M. D., Eck, M. J., Gray, N. S., and Jänne, P. A. (2022) A novel HER2-selective kinase inhibitor is effective in HER2 mutant and amplified non-small cell lung cancer. Cancer Res. 10.1158/0008-5472.CAN-21-2693
Son, J., Jang, J., Beyett, T. S., Eum, Y., Haikala, H. M., Verano, A., Lin, M., Hatcher, J. M., Kwiatkowski, N. P., Eser, P. Özden, Poitras, M. J., Wang, S., Xu, M., Gokhale, P. C., Cameron, M. D., Eck, M. J., Gray, N. S., and Jänne, P. A. (2022) A novel HER2-selective kinase inhibitor is effective in HER2 mutant and amplified non-small cell lung cancer. Cancer Res. 10.1158/0008-5472.CAN-21-2693
Thorsen, M. K., Draganova, E. B., and Heldwein, E. E. (2022) The nuclear egress complex of Epstein-Barr virus buds membranes through an oligomerization-driven mechanism. PLoS Pathog. 18, e1010623
Li, Y., Zhang, R., Wang, C., Forouhar, F., Clarke, O. B., Vorobiev, S., Singh, S., Montelione, G. T., Szyperski, T., Xu, Y., and Hunt, J. F. (2022) Oligomeric interactions maintain active-site structure in a noncooperative enzyme family. EMBO J. 10.15252/embj.2021108368
Andreev, V. I., Yu, C., Wang, J., Schnabl, J., Tirian, L., Gehre, M., Handler, D., Duchek, P., Novatchkova, M., Baumgartner, L., Meixner, K., Sienski, G., Patel, D. J., and Brennecke, J. (2022) Panoramix SUMOylation on chromatin connects the piRNA pathway to the cellular heterochromatin machinery. Nat Struct Mol Biol. 29, 130-142
Hobbs, S. J., Wein, T., Lu, A., Morehouse, B. R., Schnabel, J., Leavitt, A., Yirmiya, E., Sorek, R., and Kranzusch, P. J. (2022) Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity. Nature. 10.1038/s41586-022-04716-y
Schiltz, C. J., Wilson, J. R., Hosford, C. J., Adams, M. C., Preising, S. E., DeBlasio, S. L., MacLeod, H. J., Van Eck, J., Heck, M. L., and Chappie, J. S. (2022) Polerovirus N-terminal readthrough domain structures reveal molecular strategies for mitigating virus transmission by aphids. Nat Commun. 13, 6368
Schiltz, C. J., Wilson, J. R., Hosford, C. J., Adams, M. C., Preising, S. E., DeBlasio, S. L., MacLeod, H. J., Van Eck, J., Heck, M. L., and Chappie, J. S. (2022) Polerovirus N-terminal readthrough domain structures reveal molecular strategies for mitigating virus transmission by aphids. Nat Commun. 13, 6368
Wang, Z., Dang, H. V., Amaya, M., Xu, Y., Yin, R., Yan, L., Hickey, A. C., Annand, E. J., Horsburgh, B. A., Reid, P. A., Smith, I., Eden, J. - S., Xu, K., Broder, C. C., and Veesler, D. (2022) Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant. Proc Natl Acad Sci U S A. 119, e2122769119
Wang, Z., Dang, H. V., Amaya, M., Xu, Y., Yin, R., Yan, L., Hickey, A. C., Annand, E. J., Horsburgh, B. A., Reid, P. A., Smith, I., Eden, J. - S., Xu, K., Broder, C. C., and Veesler, D. (2022) Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant. Proc Natl Acad Sci U S A. 119, e2122769119
Zuk, A., Si, Z., Loi, S., Bommegowda, S., Hoivik, D., Danthi, S., Molnar, G., Csizmadia, V., and Rabinowitz, M. (2022) Preclinical characterization of vadadustat (AKB-6548), an oral small molecule hypoxia inducible factor prolyl-4-hydroxylase inhibitor, for the potential treatment of renal anemia. J Pharmacol Exp Ther. 10.1124/jpet.122.001126
Gero, T. W., Heppner, D. E., Beyett, T. S., To, C., Azevedo, S. C., Jang, J., Bunnell, T., Feru, F., Li, Z., Shin, B. Hee, Soroko, K. M., Gokhale, P. C., Gray, N. S., Jänne, P. A., Eck, M. J., and Scott, D. A. (2022) Quinazolinones as allosteric fourth-generation EGFR inhibitors for the treatment of NSCLC. Bioorg Med Chem Lett. 10.1016/j.bmcl.2022.128718
Hauser, B. M., Sangesland, M., St Denis, K. J., Lam, E. C., Case, J. Brett, Windsor, I. W., Feldman, J., Caradonna, T. M., Kannegieter, T., Diamond, M. S., Balazs, A. B., Lingwood, D., and Schmidt, A. G. (2022) Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting. Cell Rep. 38, 110561
Johnson, C. W., Seo, H. - S., Terrell, E. M., Yang, M. - H., KleinJan, F., Gebregiworgis, T., Gasmi-Seabrook, G. M. C., Geffken, E. A., Lakhani, J., Song, K., Bashyal, P., Popow, O., Paulo, J. A., Liu, A., Mattos, C., Marshall, C. B., Ikura, M., Morrison, D. K., Dhe-Paganon, S., and Haigis, K. M. (2022) Regulation of GTPase function by autophosphorylation. Mol Cell. 82, 950-968.e14
Hazari, A., Sawaya, M. R., Vlahakis, N., Johnstone, T. C., Boyer, D., Rodriguez, J., Eisenberg, D., and Raskatov, J. A. (2022) The rippled β-sheet layer configuration-a novel supramolecular architecture based on predictions by Pauling and Corey.. Chem Sci. 13, 8947-8952
Zeller, M. J., Favorov, O., Li, K., Nuthanakanti, A., Hussein, D., Michaud, A., Lafontaine, D. A., Busan, S., Serganov, A., Aubé, J., and Weeks, K. M. (2022) SHAPE-enabled fragment-based ligand discovery for RNA. Proc Natl Acad Sci U S A. 119, e2122660119
Spiegelman, L., Bahn-Suh, A., Montaño, E. T., Zhang, L., Hura, G. L., Patras, K. A., Kumar, A., F Tezcan, A., Nizet, V., Tsutakawa, S. E., and Ghosh, P. (2022) Strengthening of enterococcal biofilms by Esp. PLoS Pathog. 18, e1010829
Adlakha, J., Hong, Z., Li, P. Q., and Reinisch, K. M. (2022) Structural and biochemical insights into lipid transport by VPS13 proteins. J Cell Biol. 10.1083/jcb.202202030
Prew, M. S., Camara, C. M., Botzanowski, T., Moroco, J. A., Bloch, N. B., Levy, H. R., Seo, H. - S., Dhe-Paganon, S., Bird, G. H., Herce, H. D., Gygi, M. A., Escudero, S., Wales, T. E., Engen, J. R., and Walensky, L. D. (2022) Structural basis for defective membrane targeting of mutant enzyme in human VLCAD deficiency. Nat Commun. 13, 3669

Pages