Publications
(2010) Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression. Cell. 141, 1183-94
(2010) Protein-induced photophysical changes to the amyloid indicator dye thioflavin T. Proc Natl Acad Sci U S A. 107, 16863-8
(2010) Structural and mechanistic insights into cooperative assembly of dimeric Notch transcription complexes. Nat Struct Mol Biol. 17, 1312-7
(2010) The structural basis of Cryptosporidium -specific IMP dehydrogenase inhibitor selectivity. J Am Chem Soc. 132, 1230-1
(2010) Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA. Cell Cycle. 9, 3054-62
(2010) Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. J Biol Chem. 285, 13066-78
(2010) Structural determination and tryptophan fluorescence of heterokaryon incompatibility C2 protein (HET-C2), a fungal glycolipid transfer protein (GLTP), provide novel insights into glycolipid specificity and membrane interaction by the GLTP fold. J Biol Chem. 285, 13066-78
(2010) Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc Natl Acad Sci U S A. 107, 18428-32
(2010) Structural insight into the mechanisms of enveloped virus tethering by tetherin. Proc Natl Acad Sci U S A. 107, 18428-32
(2010) Structure determination and characterization of the vitamin B6 degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase. Biochemistry. 49, 1226-35
(2010) Structure determination and characterization of the vitamin B6 degradative enzyme (E)-2-(acetamidomethylene)succinate hydrolase. Biochemistry. 49, 1226-35
(2010) Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle. Science. 330, 635-41
(2010) Structure of dihydroorotase from Bacillus anthracis at 2.6 Å resolution.. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66, 1432-5
(2010) Structure of dihydroorotase from Bacillus anthracis at 2.6 Å resolution.. Acta Crystallogr Sect F Struct Biol Cryst Commun. 66, 1432-5
(2010) Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution. Science. 329, 182-6
(2009) Crystal structure of (+)-delta-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis. Biochemistry. 48, 6175-83
(2009) Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion. J Virol. 83, 4338-44
(2009) Crystal structure of human mitochondrial acyl-CoA thioesterase (ACOT2). Biochem Biophys Res Commun. 385, 630-3
(2009) Crystal structure of iodotyrosine deiodinase, a novel flavoprotein responsible for iodide salvage in thyroid glands. J Biol Chem. 284, 19659-67
(2009) Crystal structure of the ATP-gated P2X(4) ion channel in the closed state. Nature. 460, 592-8
(2009) Crystal structure of the eukaryotic strong inward-rectifier K+ channel Kir2.2 at 3.1 A resolution. Science. 326, 1668-74
(2009) Crystal structure of the membrane fusion protein CusB from Escherichia coli. J Mol Biol. 393, 342-55
(2009) Crystal structures of human SIRT3 displaying substrate-induced conformational changes. J Biol Chem. 284, 24394-405