Publications
(2018) Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity. J Biol Chem. 10.1074/jbc.RA118.003975
(2018) Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor. Structure. 26, 153-160.e4
(2018) C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc Natl Acad Sci U S A. 115, 162-167
(2018) Glucan Binding Protein C of Mediates both Sucrose-Independent and Sucrose-Dependent Adherence. Infect Immun. 10.1128/IAI.00146-18
(2018) Glucan Binding Protein C of Mediates both Sucrose-Independent and Sucrose-Dependent Adherence. Infect Immun. 10.1128/IAI.00146-18
(2018) HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope. Nat Commun. 9, 1111
(2018) HIV envelope V3 region mimic embodies key features of a broadly neutralizing antibody lineage epitope. Nat Commun. 9, 1111
(2018) Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells. Proc Natl Acad Sci U S A. 115, E886-E895
(2018) Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. J Biol Chem. 10.1074/jbc.RA118.005695
(2018) Mechanistic basis for the evolution of chalcone synthase catalytic cysteine reactivity in land plants. J Biol Chem. 10.1074/jbc.RA118.005695
(2018) Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48, 174-184.e9
(2018) Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun. 9, 5145
(2018) Monoamine Biosynthesis via a Noncanonical Calcium-Activatable Aromatic Amino Acid Decarboxylase in Psilocybin Mushroom. ACS Chem Biol. 13, 3343-3353
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. COMPPÅ Symposium on Membrane Protein Production and Analysis, June 17-19, 2018
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2018 Annual Meeting of the American Crystallographic Association, July 20-24, 2018
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Biophysical Society 62nd Annual Meeting, Feb 17-21, 2018
(2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 32nd Annual Symposium of The Protein Society; Boston, MA, July 9-12, 2018. 27 Suppl 1, 11-245
(2018) New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2). Eur J Pharm Sci. 118, 67-79
(2018) Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1. Proc Natl Acad Sci U S A. 115, E5467-E5476
(2018) Redox-dependent rearrangements of the NiFeS cluster of carbon monoxide dehydrogenase. Elife. 10.7554/eLife.39451
(2018) Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun. 9, 4147
(2018) Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism. Nat Commun. 9, 4147
(2018) The SAM domain of mouse SAMHD1 is critical for its activation and regulation. Nat Commun. 9, 411
(2018) Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth. J Clin Invest. 128, 4397-4412

