Publications
4-Methyl-1,2,3-Triazoles as -Acetyl-Lysine Mimics Afford Potent BET Bromodomain Inhibitors with Improved Selectivity. J Med Chem. 64, 10497-10511
(2021) Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain. J Virol. 95, e0186820
(2021) Atomic view of an amyloid dodecamer exhibiting selective cellular toxic vulnerability in acute brain slices. Protein Sci. 10.1002/pro.4268
(2021) Binding and Action of Triphenylphosphonium Analog of Chloramphenicol upon the Bacterial Ribosome. Antibiotics (Basel). 10.3390/antibiotics10040390
(2021) Bipartite binding of the N terminus of Skp2 to cyclin A. Structure. 10.1016/j.str.2021.04.011
(2021) cGAS-like receptors sense RNA and control 3'2'-cGAMP signaling in Drosophila. Nature. 10.1038/s41586-021-03743-5
(2021) Computational design of a synthetic PD-1 agonist. Proc Natl Acad Sci U S A. 10.1073/pnas.2102164118
(2021) Computational design of a synthetic PD-1 agonist. Proc Natl Acad Sci U S A. 10.1073/pnas.2102164118
(2021) Computational design of a synthetic PD-1 agonist. Proc Natl Acad Sci U S A. 10.1073/pnas.2102164118
(2021) Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. ACS Med Chem Lett. 12, 249-255
(2021) Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding. Structure. 29, 572-586.e6
(2021) Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding. Structure. 29, 572-586.e6
(2021) Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding. Structure. 29, 572-586.e6
(2021) Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding. Structure. 29, 572-586.e6
(2021) Crystal structure of human PACRG in complex with MEIG1 reveals roles in axoneme formation and tubulin binding. Structure. 29, 572-586.e6
(2021) (2021) (2021) Crystal structure of the Tspan15 LEL domain reveals a conserved ADAM10 binding site. Structure. 10.1016/j.str.2021.10.007
(2021) (2021) De novo design of transmembrane β barrels.. Science. 10.1126/science.abc8182
(2021) De novo design of transmembrane β barrels.. Science. 10.1126/science.abc8182
(2021) De novo design of transmembrane β barrels.. Science. 10.1126/science.abc8182
(2021) De novo protein design by deep network hallucination. Nature. 10.1038/s41586-021-04184-w
(2021) De novo protein design by deep network hallucination. Nature. 10.1038/s41586-021-04184-w
(2021) De novo protein design by deep network hallucination. Nature. 10.1038/s41586-021-04184-w
(2021)