Publications

Found 1231 results
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2014
Lee, K. Sing Steph, Liu, J. - Y., Wagner, K. M., Pakhomova, S., Dong, H., Morisseau, C., Fu, S. H., Yang, J., Wang, P., Ulu, A., Mate, C. A., Nguyen, L. V., Hwang, S. Hee, Edin, M. L., Mara, A. A., Wulff, H., Newcomer, M. E., Zeldin, D. C., and Hammock, B. D. (2014) Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy. J Med Chem. 57, 7016-30
Xu, S., Hermanson, D. J., Banerjee, S., Ghebreselasie, K., Clayton, G. M., R Garavito, M., and Marnett, L. J. (2014) Oxicams bind in a novel mode to the cyclooxygenase active site via a two-water-mediated H-bonding Network. J Biol Chem. 289, 6799-808
Tian, Y., Simanshu, D. K., Ma, J. - B., Park, J. - E., Heo, I., V Kim, N., and Patel, D. J. (2014) A phosphate-binding pocket within the platform-PAZ-connector helix cassette of human Dicer. Mol Cell. 53, 606-16
Sawaya, M. R., Cascio, D., Gingery, M., Rodriguez, J., Goldschmidt, L., Colletier, J. - P., Messerschmidt, M. M., Boutet, S., Koglin, J. E., Williams, G. J., Brewster, A. S., Nass, K., Hattne, J., Botha, S., R Doak, B., Shoeman, R. L., DePonte, D. P., Park, H. - W., Federici, B. A., Sauter, N. K., Schlichting, I., and Eisenberg, D. S. (2014) Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam.. Proc Natl Acad Sci U S A. 111, 12769-74
Zhou, L., Bosscher, M., Zhang, C., Ozçubukçu, S., Zhang, L., Zhang, W., Li, C. J., Liu, J., Jensen, M. P., Lai, L., and He, C. (2014) A protein engineered to bind uranyl selectively and with femtomolar affinity. Nat Chem. 6, 236-41
Li, R., Chou, W. K. W., Himmelberger, J. A., Litwin, K. M., Harris, G. G., Cane, D. E., and Christianson, D. W. (2014) Reprogramming the chemodiversity of terpenoid cyclization by remolding the active site contour of epi-isozizaene synthase. Biochemistry. 53, 1155-68
Li, R., Chou, W. K. W., Himmelberger, J. A., Litwin, K. M., Harris, G. G., Cane, D. E., and Christianson, D. W. (2014) Reprogramming the chemodiversity of terpenoid cyclization by remolding the active site contour of epi-isozizaene synthase. Biochemistry. 53, 1155-68
Jiménez-Osés, G., Osuna, S., Gao, X., Sawaya, M. R., Gilson, L., Collier, S. J., Huisman, G. W., Yeates, T. O., Tang, Y., and Houk, K. N. (2014) The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat Chem Biol. 10, 431-6
Jiménez-Osés, G., Osuna, S., Gao, X., Sawaya, M. R., Gilson, L., Collier, S. J., Huisman, G. W., Yeates, T. O., Tang, Y., and Houk, K. N. (2014) The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat Chem Biol. 10, 431-6
Cai, Y., Deng, Y., Horenkamp, F., Reinisch, K. M., and Burd, C. G. (2014) Sac1-Vps74 structure reveals a mechanism to terminate phosphoinositide signaling in the Golgi apparatus. J Cell Biol. 206, 485-91
Li, L., Fierer, J. O., Rapoport, T. A., and Howarth, M. (2014) Structural analysis and optimization of the covalent association between SpyCatcher and a peptide Tag. J Mol Biol. 426, 309-17
Jacobitz, A. W., Wereszczynski, J., Yi, S. Wook, Amer, B. R., Huang, G. L., Nguyen, A. V., Sawaya, M. R., Jung, M. E., J McCammon, A., and Clubb, R. T. (2014) Structural and computational studies of the Staphylococcus aureus sortase B-substrate complex reveal a substrate-stabilized oxyanion hole. J Biol Chem. 289, 8891-902
Bhattacharya, S., Lou, X., Hwang, P., Rajashankar, K. R., Wang, X., Gustafsson, J. - Å., Fletterick, R. J., Jacobson, R. H., and Webb, P. (2014) Structural and functional insight into TAF1-TAF7, a subcomplex of transcription factor II D. Proc Natl Acad Sci U S A. 111, 9103-8
Zeqiraj, E., Tang, X., Hunter, R. W., García-Rocha, M., Judd, A., Deak, M., von Wilamowitz-Moellendorff, A., Kurinov, I., Guinovart, J. J., Tyers, M., Sakamoto, K., and Sicheri, F. (2014) Structural basis for the recruitment of glycogen synthase by glycogenin. Proc Natl Acad Sci U S A. 111, E2831-40
Peisley, A., Wu, B., Xu, H., Chen, Z. J., and Hur, S. (2014) Structural basis for ubiquitin-mediated antiviral signal activation by RIG-I. Nature. 509, 110-4
Montemayor, E. J., Katolik, A., Clark, N. E., Taylor, A. B., Schuermann, J. P., D Combs, J., Johnsson, R., Holloway, S. P., Stevens, S. W., Damha, M. J., and P Hart, J. (2014) Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res. 42, 10845-55
Montemayor, E. J., Katolik, A., Clark, N. E., Taylor, A. B., Schuermann, J. P., D Combs, J., Johnsson, R., Holloway, S. P., Stevens, S. W., Damha, M. J., and P Hart, J. (2014) Structural basis of lariat RNA recognition by the intron debranching enzyme Dbr1. Nucleic Acids Res. 42, 10845-55
Johnson, Z. Lee, Lee, J. - H., Lee, K., Lee, M., Kwon, D. - Y., Hong, J., and Lee, S. - Y. (2014) Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters. Elife. 3, e03604
Li, Q., Wanderling, S., Paduch, M., Medovoy, D., Singharoy, A., McGreevy, R., Villalba-Galea, C. A., Hulse, R. E., Roux, B., Schulten, K., Kossiakoff, A., and Perozo, E. (2014) Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain. Nat Struct Mol Biol. 21, 244-52
Pemberton, T. A., Srivastava, D., Sanyal, N., Henzl, M. T., Becker, D. F., and Tanner, J. J. (2014) Structural studies of yeast Δ(1)-pyrroline-5-carboxylate dehydrogenase (ALDH4A1): active site flexibility and oligomeric state.. Biochemistry. 53, 1350-9
Feld, G. K., El-Etr, S., Corzett, M. H., Hunter, M. S., Belhocine, K., Monack, D. M., Frank, M., Segelke, B. W., and Rasley, A. (2014) Structure and function of REP34 implicates carboxypeptidase activity in Francisella tularensis host cell invasion. J Biol Chem. 289, 30668-30679
Horton, J. R., Nugent, R. L., Li, A., Mabuchi, M. Yamada, Fomenkov, A., Cohen-Karni, D., Griggs, R. M., Zhang, X., Wilson, G. G., Zheng, Y., Xu, S. - Y., and Cheng, X. (2014) Structure and mutagenesis of the DNA modification-dependent restriction endonuclease AspBHI. Sci Rep. 4, 4246
Yang, T., Liu, Q., Kloss, B., Bruni, R., Kalathur, R. C., Guo, Y., Kloppmann, E., Rost, B., Colecraft, H. M., and Hendrickson, W. A. (2014) Structure and selectivity in bestrophin ion channels. Science. 346, 355-9
Lai, Y. - T., Reading, E., Hura, G. L., Tsai, K. - L., Laganowsky, A., Asturias, F. J., Tainer, J. A., Robinson, C. V., and Yeates, T. O. (2014) Structure of a designed protein cage that self-assembles into a highly porous cube. Nat Chem. 6, 1065-71
Huang, H., Levin, E. J., Liu, S., Bai, Y., Lockless, S. W., and Zhou, M. (2014) Structure of a membrane-embedded prenyltransferase homologous to UBIAD1. PLoS Biol. 12, e1001911

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