Publications

Found 1344 results
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2018
Porter, N. J., Osko, J. D., Diedrich, D., Kurz, T., Hooker, J. M., Hansen, F. K., and Christianson, D. W. (2018) Histone Deacetylase 6-Selective Inhibitors and the Influence of Capping Groups on Hydroxamate-Zinc Denticity. J Med Chem. 10.1021/acs.jmedchem.8b01013
Hellman, L. M., Foley, K. C., Singh, N. K., Alonso, J. A., Riley, T. P., Devlin, J. R., Ayres, C. M., Keller, G. L. J., Zhang, Y., Kooi, C. W. Vander, Nishimura, M. I., and Baker, B. M. (2018) Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol Ther. 10.1016/j.ymthe.2018.12.010
Hellman, L. M., Foley, K. C., Singh, N. K., Alonso, J. A., Riley, T. P., Devlin, J. R., Ayres, C. M., Keller, G. L. J., Zhang, Y., Kooi, C. W. Vander, Nishimura, M. I., and Baker, B. M. (2018) Improving T Cell Receptor On-Target Specificity via Structure-Guided Design. Mol Ther. 10.1016/j.ymthe.2018.12.010
Choi, E. H., Suh, S., Sander, C. L., Hernandez, C. J. Ortiz, Bulman, E. R., Khadka, N., Dong, Z., Shi, W., Palczewski, K., and Kiser, P. D. (2018) Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Hum Mol Genet. 10.1093/hmg/ddy128
Choi, E. H., Suh, S., Sander, C. L., Hernandez, C. J. Ortiz, Bulman, E. R., Khadka, N., Dong, Z., Shi, W., Palczewski, K., and Kiser, P. D. (2018) Insights into the pathogenesis of dominant retinitis pigmentosa associated with a D477G mutation in RPE65. Hum Mol Genet. 10.1093/hmg/ddy128
Zeiske, T., Baburajendran, N., Kaczynska, A., Brasch, J., Palmer, A. G., Shapiro, L., Honig, B., and Mann, R. S. (2018) Intrinsic DNA Shape Accounts for Affinity Differences between Hox-Cofactor Binding Sites. Cell Rep. 24, 2221-2230
Harris, N. C., Born, D. A., Cai, W., Huang, Y., Martin, J., Khalaf, R., Drennan, C. L., and Zhang, W. (2018) Isonitrile Formation by a Non-Heme Iron(II)-Dependent Oxidase/Decarboxylase. Angew Chem Int Ed Engl. 57, 9707-9710
Araghi, R. Rezaei, Bird, G. H., Ryan, J. A., Jenson, J. M., Godes, M., Pritz, J. R., Grant, R. A., Letai, A., Walensky, L. D., and Keating, A. E. (2018) Iterative optimization yields Mcl-1-targeting stapled peptides with selective cytotoxicity to Mcl-1-dependent cancer cells. Proc Natl Acad Sci U S A. 115, E886-E895
Bailey, L. J., Sheehy, K. M., Dominik, P. K., Liang, W. G., Rui, H., Clark, M., Jaskolowski, M., Kim, Y., Deneka, D., Tang, W. - J., and Kossiakoff, A. A. (2018) Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol. 430, 337-347
Bailey, L. J., Sheehy, K. M., Dominik, P. K., Liang, W. G., Rui, H., Clark, M., Jaskolowski, M., Kim, Y., Deneka, D., Tang, W. - J., and Kossiakoff, A. A. (2018) Locking the Elbow: Improved Antibody Fab Fragments as Chaperones for Structure Determination. J Mol Biol. 430, 337-347
Melnikov, S. V., Khabibullina, N. F., Mairhofer, E., Vargas-Rodriguez, O., Reynolds, N. M., Micura, R., Söll, D., and Polikanov, Y. S. (2018) Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site. Nucleic Acids Res. 10.1093/nar/gky1211
Dionne, G., Qiu, X., Rapp, M., Liang, X., Zhao, B., Peng, G., Katsamba, P. S., Ahlsen, G., Rubinstein, R., Potter, C. S., Carragher, B., Honig, B., Müller, U., and Shapiro, L. (2018) Mechanotransduction by PCDH15 Relies on a Novel cis-Dimeric Architecture. Neuron. 99, 480-492.e5
Lavoie, H., Sahmi, M., Maisonneuve, P., Marullo, S. A., Thevakumaran, N., Jin, T., Kurinov, I., Sicheri, F., and Therrien, M. (2018) MEK drives BRAF activation through allosteric control of KSR proteins. Nature. 10.1038/nature25478
McCarthy, K. R., Watanabe, A., Kuraoka, M., Do, K. T., McGee, C. E., Sempowski, G. D., Kepler, T. B., Schmidt, A. G., Kelsoe, G., and Harrison, S. C. (2018) Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48, 174-184.e9
McCarthy, K. R., Watanabe, A., Kuraoka, M., Do, K. T., McGee, C. E., Sempowski, G. D., Kepler, T. B., Schmidt, A. G., Kelsoe, G., and Harrison, S. C. (2018) Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48, 174-184.e9
McCarthy, K. R., Watanabe, A., Kuraoka, M., Do, K. T., McGee, C. E., Sempowski, G. D., Kepler, T. B., Schmidt, A. G., Kelsoe, G., and Harrison, S. C. (2018) Memory B Cells that Cross-React with Group 1 and Group 2 Influenza A Viruses Are Abundant in Adult Human Repertoires. Immunity. 48, 174-184.e9
Porter, N. J., Shen, S., Barinka, C., Kozikowski, A. P., and Christianson, D. W. (2018) Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor. ACS Med Chem Lett. 9, 1301-1305
Chen, W., Mandali, S., Hancock, S. P., Kumar, P., Collazo, M., Cascio, D., and Johnson, R. C. (2018) Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS-family transposition. Elife. 10.7554/eLife.39611
Kourinov, I., Capel, M., Banerjee, S., A. Lynch, E., Murphy, F., Neau, D., Perry, K., Rajashankar, K., Salbego, C., Schuermann, J., Sukumar, N., Withrow, J., and Ealick, S. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2018 Annual Meeting of the American Crystallographic Association, July 20-24, 2018
Banerjee, S., Capel, M., Kourinov, I., Lynch, A., Murphy, F., Neau, D., Perry, K., Rajashankar, K., Salbego, C., Schuermann, J., Sukumar, N., Withrow, J., and Ealick, S. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. COMPPÅ Symposium on Membrane Protein Production and Analysis, June 17-19, 2018
Perry, K., Capel, M., Banerjee, S., Kourinov, I., A. Lynch, E., Murphy, F., Neau, D., Rajashankar, K.  R., Salbego, C., Schuermann, J. P., Sukumar, N., Withrow, J., and Ealick, S. E. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 32nd Annual Symposium of The Protein Society; Boston, MA, July 9-12, 2018. 27 Suppl 1, 11-245
Banerjee, S., Capel, M., Kourinov, I., A. Lynch, E., Murphy, F., Neau, D., Perry, K., Salbego, C., Rajashankar, K.  R., Schuermann, J., Sukumar, N., Withrow, J., and Ealick, S. E. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Biophysical Society 62nd Annual Meeting, Feb 17-21, 2018
Cosmanescu, F., Katsamba, P. S., Sergeeva, A. P., Ahlsen, G., Patel, S. D., Brewer, J. J., Tan, L., Xu, S., Xiao, Q., Nagarkar-Jaiswal, S., Nern, A., Bellen, H. J., S Zipursky, L., Honig, B., and Shapiro, L. (2018) Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron. 100, 1385-1400.e6
Ragwan, E. R., Arai, E., and Kung, Y. (2018) New Crystallographic Snapshots of Large Domain Movements in Bacterial 3-Hydroxy-3-methylglutaryl Coenzyme A Reductase. Biochemistry. 57, 5715-5725
Ribeiro, C. J. A., Kankanala, J., Shi, K., Kurahashi, K., Kiselev, E., Ravji, A., Pommier, Y., Aihara, H., and Wang, Z. (2018) New fluorescence-based high-throughput screening assay for small molecule inhibitors of tyrosyl-DNA phosphodiesterase 2 (TDP2). Eur J Pharm Sci. 118, 67-79

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