Publications
(2013) A structural study of ion permeation in OmpF porin from anomalous X-ray diffraction and molecular dynamics simulations. J Am Chem Soc. 135, 16561-8
(2013) Structure of a bimodular botulinum neurotoxin complex provides insights into its oral toxicity. PLoS Pathog. 9, e1003690
(2013) Structure of a pseudokinase-domain switch that controls oncogenic activation of Jak kinases. Nat Struct Mol Biol. 20, 1221-3
(2013) Structure of the Toxoplasma gondii ROP18 kinase domain reveals a second ligand binding pocket required for acute virulence. J Biol Chem. 288, 34968-80
(2013) Structure of the uracil complex of Vaccinia virus uracil DNA glycosylase. Acta Crystallogr Sect F Struct Biol Cryst Commun. 69, 1328-34
(2013) Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. Nat Struct Mol Biol. 20, 740-7
(2013) A substrate access tunnel in the cytosolic domain is not an essential feature of the solute carrier 4 (SLC4) family of bicarbonate transporters. J Biol Chem. 288, 33848-60
(2013) Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors. Bioorg Med Chem Lett. 23, 417-21
(2014) Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol Cell. 56, 531-40
(2014) c-di-AMP binds the ydaO riboswitch in two pseudo-symmetry-related pockets. Nat Chem Biol. 10, 780-6
(2014) Characterization of selective exosite-binding inhibitors of matrix metalloproteinase 13 that prevent articular cartilage degradation in vitro. J Med Chem. 57, 9598-611
(2014) The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins. Dev Cell. 31, 487-502
(2014) The chromosome axis controls meiotic events through a hierarchical assembly of HORMA domain proteins. Dev Cell. 31, 487-502
(2014) The class III ribonucleotide reductase from Neisseria bacilliformis can utilize thioredoxin as a reductant. Proc Natl Acad Sci U S A. 111, E3756-65
(2014) Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc Natl Acad Sci U S A. 111, E4551-9
(2014) Computational design of a red fluorophore ligase for site-specific protein labeling in living cells. Proc Natl Acad Sci U S A. 111, E4551-9
(2014) Crystal structure of the Campylobacter jejuni CmeC outer membrane channel. Protein Sci. 23, 954-61
(2014) Crystal structure of the Campylobacter jejuni CmeC outer membrane channel. Protein Sci. 23, 954-61
(2014) Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump. PLoS One. 9, e97903
(2014) Crystal structure of the Neisseria gonorrhoeae MtrD inner membrane multidrug efflux pump. PLoS One. 9, e97903
(2014) Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. PLoS One. 9, e97475
(2014) Crystal structure of the open state of the Neisseria gonorrhoeae MtrE outer membrane channel. PLoS One. 9, e97475