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2018

Dionne, G., Qiu, X., Rapp, M., Liang, X., Zhao, B., Peng, G., Katsamba, P. S., Ahlsen, G., Rubinstein, R., Potter, C. S., Carragher, B., Honig, B., Müller, U., and Shapiro, L. (2018) Mechanotransduction by PCDH15 Relies on a Novel cis-Dimeric Architecture. Neuron. 99, 480-492.e5

Shen, G., Li, S., Cui, W., Liu, S., Yang, Y., Gross, M., and Li, W. (2018) Membrane Protein Structure in Live Cells: Methodology for Studying Drug Interaction by Mass Spectrometry-Based Footprinting. Biochemistry. 57, 286-294

Thompson, M. C., Cascio, D., and Yeates, T. O. (2018) Microfocus diffraction from different regions of a protein crystal: structural variations and unit-cell polymorphism. Acta Crystallogr D Struct Biol. 74, 411-421

Porter, N. J., Shen, S., Barinka, C., Kozikowski, A. P., and Christianson, D. W. (2018) Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor. ACS Med Chem Lett. 9, 1301-1305

Lv, Z., Yuan, L., Atkison, J. H., Williams, K. M., Vega, R., E Sessions, H., Divlianska, D. B., Davies, C., Chen, Y., and Olsen, S. K. (2018) Molecular mechanism of a covalent allosteric inhibitor of SUMO E1 activating enzyme. Nat Commun. 9, 5145

Torrens-Spence, M. Patrick, Liu, C. - T., Pluskal, T., Chung, Y. Kwan, and Weng, J. - K. (2018) Monoamine Biosynthesis via a Noncanonical Calcium-Activatable Aromatic Amino Acid Decarboxylase in Psilocybin Mushroom. ACS Chem Biol. 13, 3343-3353

Chen, W., Mandali, S., Hancock, S. P., Kumar, P., Collazo, M., Cascio, D., and Johnson, R. C. (2018) Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS-family transposition. Elife. 10.7554/eLife.39611

Chen, W., Mandali, S., Hancock, S. P., Kumar, P., Collazo, M., Cascio, D., and Johnson, R. C. (2018) Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS-family transposition. Elife. 10.7554/eLife.39611

Chen, W., Mandali, S., Hancock, S. P., Kumar, P., Collazo, M., Cascio, D., and Johnson, R. C. (2018) Multiple serine transposase dimers assemble the transposon-end synaptic complex during IS-family transposition. Elife. 10.7554/eLife.39611

Kourinov, I., Capel, M., Banerjee, S., A. Lynch, E., Murphy, F., Neau, D., Perry, K., Rajashankar, K., Salbego, C., Schuermann, J., Sukumar, N., Withrow, J., and Ealick, S. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. 2018 Annual Meeting of the American Crystallographic Association, July 20-24, 2018

Banerjee, S., Capel, M., Kourinov, I., Lynch, A., Murphy, F., Neau, D., Perry, K., Rajashankar, K., Salbego, C., Schuermann, J., Sukumar, N., Withrow, J., and Ealick, S. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. COMPPÅ Symposium on Membrane Protein Production and Analysis, June 17-19, 2018

Perry, K., Capel, M., Banerjee, S., Kourinov, I., A. Lynch, E., Murphy, F., Neau, D., Rajashankar, K. R., Salbego, C., Schuermann, J. P., Sukumar, N., Withrow, J., and Ealick, S. E. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Award Winners and Abstracts of the 32nd Annual Symposium of The Protein Society; Boston, MA, July 9-12, 2018. 27 Suppl 1, 11-245

Banerjee, S., Capel, M., Kourinov, I., A. Lynch, E., Murphy, F., Neau, D., Perry, K., Salbego, C., Rajashankar, K. R., Schuermann, J., Sukumar, N., Withrow, J., and Ealick, S. E. (2018) NE-CAT: Crystallography Beamlines for Challenging Structural Biology Research. Biophysical Society 62nd Annual Meeting, Feb 17-21, 2018

Cosmanescu, F., Katsamba, P. S., Sergeeva, A. P., Ahlsen, G., Patel, S. D., Brewer, J. J., Tan, L., Xu, S., Xiao, Q., Nagarkar-Jaiswal, S., Nern, A., Bellen, H. J., S Zipursky, L., Honig, B., and Shapiro, L. (2018) Neuron-Subtype-Specific Expression, Interaction Affinities, and Specificity Determinants of DIP/Dpr Cell Recognition Proteins. Neuron. 100, 1385-1400.e6

Kourinov, I., Capel, M., Banerjee, S., Murphy, F., Neau, D., Perry, K., Rajashankar, K., Schuermann, J., Sukumar, N., and Ealick, S. (2018) Northeastern Collaborative Access Team (NE-CAT) crystallography beamlines for challenging structural biology research. Acta Crystallographica Section A Foundations and Advances. 74, a97-a97

Muok, A. R., Chua, T. Khiang, Le, H., and Crane, B. R. (2018) Nucleotide Spin Labeling for ESR Spectroscopy of ATP-Binding Proteins. Applied Magnetic ResonanceApplied Magnetic Resonance. 49, 1385-1395

Muok, A. R., Chua, T. Khiang, Le, H., and Crane, B. R. (2018) Nucleotide Spin Labeling for ESR Spectroscopy of ATP-Binding Proteins. Applied Magnetic ResonanceApplied Magnetic Resonance. 49, 1385-1395

Pantel, L., Florin, T., Dobosz-Bartoszek, M., Racine, E., Sarciaux, M., Serri, M., Houard, J., Campagne, J. - M., de Figueiredo, R. Marcia, Midrier, C., Gaudriault, S., Givaudan, A., Lanois, A., Forst, S., Aumelas, A., Cotteaux-Lautard, C., Bolla, J. - M., Lundberg, C. Vingsbo, Huseby, D. L., Hughes, D., Villain-Guillot, P., Mankin, A. S., Polikanov, Y. S., and Gualtieri, M. (2018) Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site. Mol Cell. 70, 83-94.e7

Pantel, L., Florin, T., Dobosz-Bartoszek, M., Racine, E., Sarciaux, M., Serri, M., Houard, J., Campagne, J. - M., de Figueiredo, R. Marcia, Midrier, C., Gaudriault, S., Givaudan, A., Lanois, A., Forst, S., Aumelas, A., Cotteaux-Lautard, C., Bolla, J. - M., Lundberg, C. Vingsbo, Huseby, D. L., Hughes, D., Villain-Guillot, P., Mankin, A. S., Polikanov, Y. S., and Gualtieri, M. (2018) Odilorhabdins, Antibacterial Agents that Cause Miscoding by Binding at a New Ribosomal Site. Mol Cell. 70, 83-94.e7

Dong, M., Kathiresan, V., Fenwick, M. K., Torelli, A. T., Zhang, Y., Caranto, J. D., Dzikovski, B., Sharma, A., Lancaster, K. M., Freed, J. H., Ealick, S. E., Hoffman, B. M., and Lin, H. (2018) Organometallic and radical intermediates reveal mechanism of diphthamide biosynthesis. Science. 359, 1247-1250

Alex, J. M., Rennie, M. L., Volpi, S., Sansone, F., Casnati, A., and Crowley, P. B. (2018) Phosphonated Calixarene as a "Molecular Glue" for Protein Crystallization. Crystal Growth & DesignCryst. Growth Des. 18, 2467-2473

Alex, J. M., Rennie, M. L., Volpi, S., Sansone, F., Casnati, A., and Crowley, P. B. (2018) Phosphonated Calixarene as a "Molecular Glue" for Protein Crystallization. Crystal Growth & DesignCryst. Growth Des. 18, 2467-2473

Hammill, J. T., Scott, D. C., Min, J., Connelly, M. C., Holbrook, G., Zhu, F., Matheny, A., Yang, L., Singh, B., Schulman, B. A., and R Guy, K. (2018) Piperidinyl Ureas Chemically Control Defective in Cullin Neddylation 1 (DCN1)-Mediated Cullin Neddylation. J Med Chem. 61, 2680-2693

Qi, J., Li, X., Peng, H., Cook, E. M., Dadashian, E. L., Wiestner, A., Park, H. J., and Rader, C. (2018) Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1. Proc Natl Acad Sci U S A. 115, E5467-E5476

Novikova, I. V., Sharma, N., Moser, T., Sontag, R., Liu, Y., Collazo, M. J., Cascio, D., Shokuhfar, T., Hellmann, H., Knoblauch, M., and Evans, J. E. (2018) Protein structural biology using cell-free platform from wheat germ. Adv Struct Chem Imaging. 4, 13

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The Northeastern Collaborative Access Team (NE-CAT) facility at the Advanced Photon Source at Argonne National Laboratory is managed by Cornell University and consists of eight member institutions:

Columbia University
Cornell University
Genentech
Harvard University
Memorial Sloan-Kettering Cancer Center
Massachusetts Institute of Technology
Rockefeller University
Yale University

Primary funding for this project comes from the National Institute of General Medical Sciences (NIGMS), a division of the National Institutes of Health (NIH). Additional financial support for NE-CAT comes from the member institutions.