Publications

Found 68 results
Filters: Author is Drennan, Catherine L  [Clear All Filters]
2019
Feliciano, P. R., and Drennan, C. L. (2019) Structural and Biochemical Investigations of the [4Fe-4S] Cluster-Containing Fumarate Hydratase from . Biochemistry. 58, 5011-5021
Wittenborn, E. C., Cohen, S. E., Merrouch, M., Léger, C., Fourmond, V., Dementin, S., and Drennan, C. L. (2019) Structural insight into metallocofactor maturation in carbon monoxide dehydrogenase. J Biol Chem. 294, 13017-13026
Rizzolo, K., Cohen, S. E., Weitz, A. C., Muñoz, M. M. López, Hendrich, M. P., Drennan, C. L., and Elliott, S. J. (2019) A widely distributed diheme enzyme from Burkholderia that displays an atypically stable bis-Fe(IV) state. Nat Commun. 10, 1101
Chen, P. Yang- Ting, DeColli, A. A., Meyers, C. L. Freel, and Drennan, C. L. (2019) X-ray crystallography-based structural elucidation of enzyme-bound intermediates along the 1-deoxy-d-xylulose 5-phosphate synthase reaction coordinate. J Biol Chem. 294, 12405-12414
2020
Jonnalagadda, R., Flores, A. Del Rio, Cai, W., Mehmood, R., Narayanamoorthy, M., Ren, C., Zaragoza, J. Paulo T., Kulik, H. J., Zhang, W., and Drennan, C. L. (2020) Biochemical and crystallographic investigations into isonitrile formation by a non-heme iron-dependent oxidase/decarboxylase. J Biol Chem. 10.1074/jbc.RA120.015932
Cohen, S. E., Can, M., Wittenborn, E. C., Hendrickson, R. A., Ragsdale, S. W., and Drennan, C. L. (2020) Crystallographic Characterization of the Carbonylated A-Cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase. ACS Catal. 10, 9741-9746
Bollenbach, M., Ortega, M., Orman, M., Drennan, C. L., and Balskus, E. P. (2020) Discovery of a Cyclic Choline Analog That Inhibits Anaerobic Choline Metabolism by Human Gut Bacteria. ACS Med Chem Lett. 11, 1980-1985
Backman, L. Rf, Huang, Y. Y., Andorfer, M. C., Gold, B., Raines, R. T., Balskus, E. P., and Drennan, C. L. (2020) Molecular basis for catabolism of the abundant metabolite -4-hydroxy-L-proline by a microbial glycyl radical enzyme. Elife. 10.7554/eLife.51420
Wittenborn, E. C., Guendon, C., Merrouch, M., Benvenuti, M., Fourmond, V., Léger, C., Drennan, C. L., and Dementin, S. (2020) The Solvent-Exposed Fe-S D-Cluster Contributes to Oxygen-Resistance in Ni-Fe Carbon Monoxide Dehydrogenase. ACS Catal. 10, 7328-7335
Rizzolo, K., Weitz, A. C., Cohen, S. E., Drennan, C. L., Hendrich, M. P., and Elliott, S. J. (2020) A Stable Ferryl Porphyrin at the Active Site of Y463M BthA. J Am Chem Soc. 142, 11978-11982
2021
Feliciano, P. R., Carroll, K. S., and Drennan, C. L. (2021) Crystal Structure of the [4Fe-4S] Cluster-Containing Adenosine-5'-phosphosulfate Reductase from Mycobacterium tuberculosis . ACS Omega. 6, 13756-13765
Dawson, C. D., Irwin, S. M., Backman, L. R. F., Le, C., Wang, J. X., Vennelakanti, V., Yang, Z., Kulik, H. J., Drennan, C. L., and Balskus, E. P. (2021) Molecular basis of C-S bond cleavage in the glycyl radical enzyme isethionate sulfite-lyase. Cell Chem Biol. 10.1016/j.chembiol.2021.03.001
2022
Biester, A., Dementin, S., and Drennan, C. L. (2022) Visualizing the gas channel of a monofunctional carbon monoxide dehydrogenase. J Inorg Biochem. 230, 111774
2023
Adak, S., Ye, N., Calderone, L. A., Schäfer, R. J. B., Lukowski, A. L., Pandelia, M. - E., Drennan, C. L., and Moore, B. S. (2023) Oxidative rearrangement of tryptophan to indole nitrile by a single diiron enzyme. bioRxiv. 10.1101/2023.08.03.551874
Vaccaro, F. A., Born, D. A., and Drennan, C. L. (2023) Structure of metallochaperone in complex with the cobalamin-binding domain of its target mutase provides insight into cofactor delivery. Proc Natl Acad Sci U S A. 120, e2214085120
2024
Funk, M. A., Zimanyi, C. M., Andree, G. A., Hamilos, A. E., and Drennan, C. L. (2024) How ATP and dATP Act as Molecular Switches to Regulate Enzymatic Activity in the Prototypical Bacterial Class Ia Ribonucleotide Reductase. Biochemistry. 63, 2517-2531
Coco, L. B., Toci, E. M., Chen, P. Yang- Ting, Drennan, C. L., and Meyers, C. L. Freel (2024) Potent Inhibition of DXP Synthase by a -Diaryl Bisubstrate Analog. ACS Infect Dis. 10, 1312-1326
Adak, S., Ye, N., Calderone, L. A., Duan, M., Lubeck, W., Schäfer, R. J. B., Lukowski, A. L., Houk, K. N., Pandelia, M. - E., Drennan, C. L., and Moore, B. S. (2024) A single diiron enzyme catalyses the oxidative rearrangement of tryptophan to indole nitrile. Nat Chem. 16, 1989-1998

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