Publications

Found 6 results
Filters: Author is Huxford, Tom  [Clear All Filters]
2024
Mealka, M., Sierra, N. A., Matteo, D. Avellaneda, Albekioni, E., Khoury, R., Mai, T., Conley, B. M., Coleman, N. J., Sabo, K. A., Komives, E. A., Bobkov, A. A., Cooksy, A. L., Silletti, S., Schiffer, J. M., Huxford, T., and Sohl, C. D. (2024) Active site remodeling in tumor-relevant IDH1 mutants drives distinct kinetic features and potential resistance mechanisms. Nat Commun. 15, 3785
2023
Zhu, N., Mealka, M., Mitchel, S., Milani, C., Acuña, L. M., Rogers, E., Lahana, A. N., and Huxford, T. (2023) X-ray Crystallographic Study of Preferred Spacing by the NF-κB p50 Homodimer on κB DNA.. Biomolecules. 10.3390/biom13091310
2019
Maniaci, B., Lipper, C. H., Anipindi, D. L., Erlandsen, H., Cole, J. L., Stec, B., Huxford, T., and Love, J. J. (2019) Design of High-Affinity Metal-Controlled Protein Dimers. Biochemistry. 58, 2199-2207
Caldwell, J. T., Mermelstein, D. J., Walker, R. C., Bernstein, S. I., and Huxford, T. (2019) X-ray crystallographic and molecular dynamic analyses of Drosophila melanogaster embryonic muscle myosin define domains responsible for isoform-specific properties. J Mol Biol. 10.1016/j.jmb.2019.11.013
2016
Geronimo, I., Denning, C. A., W Rogers, E., Othman, T., Huxford, T., Heidary, D. K., Glazer, E. C., and Payne, C. M. (2016) Effect of Mutation and Substrate Binding on the Stability of Cytochrome P450BM3 Variants. Biochemistry. 55, 3594-606
2013
Polley, S., Bin Huang, D. -, Hauenstein, A. V., Fusco, A. J., Zhong, X., Vu, D., Schröfelbauer, B., Kim, Y., Hoffmann, A., Verma, I. M., Ghosh, G., and Huxford, T. (2013) A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation.. PLoS Biol. 11, e1001581