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Filters: Author is Rudolph, Michael J  [Clear All Filters]
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Rudolph, M. J., Chen, Y., Vorauer, C., Vance, D. J., Piazza, C. Lyn, Willsey, G. G., McCarthy, K., Muriuki, B., Cavacini, L. A., Guttman, M., and Mantis, N. J. (2024) Structure of a Human Monoclonal Antibody in Complex with Outer Surface Protein C of the Lyme Disease Spirochete, Borreliella burgdorferi. J Immunol. 213, 1234-1243
Rudolph, M. J., Czajka, T. F., Davis, S. A., Nguyen, C. My Thi, Li, X. - P., Tumer, N. E., Vance, D. J., and Mantis, N. J. (2020) Intracellular Neutralization of Ricin Toxin by Single-domain Antibodies Targeting the Active Site. J Mol Biol. 10.1016/j.jmb.2020.01.006
Rudolph, M. J., Tsymbal, A. M., Dutta, A., Davis, S. A., Algava, B., Roberge, J. Y., Tumer, N. E., and Li, X. - P. (2024) Fragment Screening to Identify Inhibitors Targeting Ribosome Binding of Shiga Toxin 2. ACS Infect Dis. 10.1021/acsinfecdis.4c00224
Rudolph, M. J., Vance, D. J., Kelow, S., Angalakurthi, S. Krishna, Nguyen, S., Davis, S. A., Rong, Y., C Middaugh, R., Weis, D. D., Dunbrack, R., Karanicolas, J., and Mantis, N. J. (2018) Contribution of an unusual CDR2 element of a single domain antibody in ricin toxin binding affinity and neutralizing activity. Protein Eng Des Sel. 10.1093/protein/gzy022
Rudolph, M. J., Dutta, A., Tsymbal, A. M., McLaughlin, J. E., Chen, Y., Davis, S. A., Theodorous, S. A., Pierce, M., Algava, B., Zhang, X., Szekely, Z., Roberge, J. Y., Li, X. - P., and Tumer, N. E. (2024) Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg Med Chem. 100, 117614
Rudolph, M. J., Vance, D. J., Cassidy, M. S., Rong, Y., and Mantis, N. J. (2017) Structural Analysis of Single Domain Antibodies Bound to a Second Neutralizing Hot Spot on Ricin Toxin's Enzymatic Subunit. J Biol Chem. 292, 872-883
Rudolph, M. J., Davis, S. A., Haque, H. M. Emranul, Ejemel, M., Cavacini, L. A., Vance, D. J., Willsey, G. G., Piazza, C. Lyn, Weis, D. D., Wang, Y., and Mantis, N. J. (2023) Structure of a transmission blocking antibody in complex with Outer surface protein A from the Lyme disease spirochete, Borreliella burgdorferi. Proteins. 10.1002/prot.26549
Rudolph, M. J., Davis, S. A., Haque, H. M. Emranul, Weis, D. D., Vance, D. J., Piazza, C. Lyn, Ejemel, M., Cavacini, L., Wang, Y., M Mbow, L., Gilmore, R. D., and Mantis, N. J. (2023) Structural Elucidation of a Protective B Cell Epitope on Outer Surface Protein C (OspC) of the Lyme Disease Spirochete, Borreliella burgdorferi. mBio. 10.1128/mbio.02981-22