Publications

Found 2919 results
2024
Rudolph, M. J., Chen, Y., Vorauer, C., Vance, D. J., Piazza, C. Lyn, Willsey, G. G., McCarthy, K., Muriuki, B., Cavacini, L. A., Guttman, M., and Mantis, N. J. (2024) Structure of a Human Monoclonal Antibody in Complex with Outer Surface Protein C of the Lyme Disease Spirochete, Borreliella burgdorferi. J Immunol. 213, 1234-1243
Nemri, J., Morales, C., Gilbert, N. C., Majewski, J., Newcomer, M. E., and Zanden, C. M. Vander (2024) Structure of a model lipid membrane oxidized by human 15-lipoxygenase-2. Biochem Biophys Res Commun. 737, 150533
Voland, R. W., Coleman, R. E., and Lancaster, K. M. (2024) The structure of Mn(II)-bound Rubisco from Spinacia oleracea. J Inorg Biochem. 260, 112682
Chen, E., Trajkovski, M., Lee, H. Kyung, Nyovanie, S., Martin, K. N., Dean, W. L., Tahiliani, M., Plavec, J., and Yatsunyk, L. A. (2024) Structure of native four-repeat satellite III sequence with non-canonical base interactions. Nucleic Acids Res. 52, 3390-3405
Ojha, M., Vogt, J., Das, N. Krishna, Redmond, E., Singh, K., Banna, H. Al, Sadat, T., and Koirala, D. (2024) Structure of saguaro cactus virus 3' translational enhancer mimics 5' cap for eIF4E binding. Proc Natl Acad Sci U S A. 121, e2313677121
Gogar, R. K., Chhikara, N., Vo, M., Gilbert, N. C., Dunkle, J. A., and Frantom, P. A. (2024) The structure of the SufS-SufE complex reveals interactions driving protected persulfide transfer in iron-sulfur cluster biogenesis. J Biol Chem. 300, 107641
Gilleran, J. A., Ashraf, K., Delvillar, M., Eck, T., Fondekar, R., Miller, E. B., Hutchinson, A., Dong, A., Seitova, A., De Souza, M. Laureano, Augeri, D., Halabelian, L., Siekierka, J., Rotella, D. P., Gordon, J., Childers, W. E., Grier, M. C., Staker, B. L., Roberge, J. Y., and Bhanot, P. (2024) Structure-Activity Relationship of a Pyrrole Based Series of PfPKG Inhibitors as Anti-Malarials. J Med Chem. 67, 3467-3503
Rudolph, M. J., Dutta, A., Tsymbal, A. M., McLaughlin, J. E., Chen, Y., Davis, S. A., Theodorous, S. A., Pierce, M., Algava, B., Zhang, X., Szekely, Z., Roberge, J. Y., Li, X. - P., and Tumer, N. E. (2024) Structure-based design and optimization of a new class of small molecule inhibitors targeting the P-stalk binding pocket of ricin. Bioorg Med Chem. 100, 117614
Li, X. - P., Rudolph, M. J., Chen, Y., and Tumer, N. E. (2024) Structure-Function Analysis of the A1 Subunit of Shiga Toxin 2 with Peptides That Target the P-Stalk Binding Site and Inhibit Activity. Biochemistry. 63, 893-905
Radakovic, A., Lewicka, A., Todisco, M., Aitken, H. R. M., Weiss, Z., Kim, S., Bannan, A., Piccirilli, J. A., and Szostak, J. W. (2024) Structure-guided aminoacylation and assembly of chimeric RNAs. bioRxiv. 10.1101/2024.03.02.583109
Meador, K., Castells-Graells, R., Aguirre, R., Sawaya, M. R., Arbing, M. A., Sherman, T., Senarathne, C., and Yeates, T. O. (2024) A suite of designed protein cages using machine learning and protein fragment-based protocols. Structure. 10.1016/j.str.2024.02.017
Lu, X., Passalacqua, L. F. M., Nodwell, M., Kong, K. Y. S., Caballero-García, G., Dolgosheina, E. V., Ferré-D'Amaré, A. R., Britton, R., and Unrau, P. J. (2024) Symmetry breaking of fluorophore binding to a G-quadruplex generates an RNA aptamer with picomolar KD. Nucleic Acids Res. 52, 8039-8051
Banayan, N. E., Loughlin, B. J., Singh, S., Forouhar, F., Lu, G., Wong, K. - H., Neky, M., Hunt, H. S., Bateman, L. B., Tamez, A., Handelman, S. K., W Price, N., and Hunt, J. F. (2024) Systematic enhancement of protein crystallization efficiency by bulk lysine-to-arginine (KR) substitution. Protein Sci. 33, e4898
Zhang, H., Sim, G. Y., Kehling, A. C., Adhav, V. Annasaheb, Savidge, A., Pastore, B., Tang, W., and Nakanishi, K. (2024) Target cleavage and gene silencing by Argonautes with cityRNAs. Cell Rep. 43, 114806
Chen, J., Zehr, E. A., Gruschus, J. M., Szyk, A., Liu, Y., Tanner, M. E., Tjandra, N., and Roll-Mecak, A. (2024) Tubulin code eraser CCP5 binds branch glutamates by substrate deformation. Nature. 631, 905-912
Draganova, E. B., Wang, H., Wu, M., Liao, S., Vu, A., Del Pino, G. L. Gonzalez, Z Zhou, H., Roller, R. J., and Heldwein, E. E. (2024) The universal suppressor mutation restores membrane budding defects in the HSV-1 nuclear egress complex by stabilizing the oligomeric lattice. PLoS Pathog. 20, e1011936
Agdanowski, M. P., Castells-Graells, R., Sawaya, M. R., Cascio, D., Yeates, T. O., and Arbing, M. A. (2024) X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. Acta Crystallogr F Struct Biol Commun. 80, 107-115
Li, Z., Lu, W., Beyett, T. S., Ficarro, S. B., Jiang, J., Tse, J., Kim, A. Yong- Ju, Marto, J. A., Che, J., Jänne, P. A., Eck, M. J., Zhang, T., and Gray, N. S. (2024) ZNL0325, a Pyrazolopyrimidine-Based Covalent Probe, Demonstrates an Alternative Binding Mode for Kinases. J Med Chem. 67, 2837-2848
2023
Li, Z., Wang, S., Nattermann, U., Bera, A. K., Borst, A. J., Yaman, M. Y., Bick, M. J., Yang, E. C., Sheffler, W., Lee, B., Seifert, S., Hura, G. L., Nguyen, H., Kang, A., Dalal, R., Lubner, J. M., Hsia, Y., Haddox, H., Courbet, A., Dowling, Q., Miranda, M., Favor, A., Etemadi, A., Edman, N. I., Yang, W., Weidle, C., Sankaran, B., Negahdari, B., Ross, M. B., Ginger, D. S., and Baker, D. (2023) Accurate computational design of three-dimensional protein crystals. Nat Mater. 10.1038/s41563-023-01683-1
Mikhaylov, V., Brambley, C. A., Keller, G. L. J., Arbuiso, A. G., Weiss, L. I., Baker, B. M., and Levine, A. J. (2023) Accurate modeling of peptide-MHC structures with AlphaFold. Structure. 10.1016/j.str.2023.11.011
Lu-Culligan, W. J., Connor, L. J., Xie, Y., Ekundayo, B. E., Rose, B. T., Machyna, M., Pintado-Urbanc, A. P., Zimmer, J. T., Vock, I. W., Bhanu, N. V., King, M. C., Garcia, B. A., Bleichert, F., and Simon, M. D. (2023) Acetyl-methyllysine marks chromatin at active transcription start sites. Nature. 622, 173-179
Tei, R., Bagde, S. R., J Fromme, C., and Baskin, J. M. (2023) Activity-based directed evolution of a membrane editor in mammalian cells. Nat Chem. 15, 1030-1039
Henneberg, L. T., Singh, J., Duda, D. M., Baek, K., Yanishevski, D., Murray, P. J., Mann, M., Sidhu, S. S., and Schulman, B. A. (2023) Activity-based profiling of cullin-RING E3 networks by conformation-specific probes. Nat Chem Biol. 19, 1513-1523
Yang, M. Hee, Tran, T. H., Hunt, B., Agnor, R., Johnson, C. W., Shui, B., Waybright, T. J., Nowak, J. A., Stephen, A. G., Simanshu, D. K., and Haigis, K. M. (2023) Allosteric Regulation of Switch-II Domain Controls KRAS Oncogenicity. Cancer Res. 83, 3176-3183
Hobbs, K. F., Propp, J., Vance, N. R., Kalenkiewicz, A., Witkin, K. R., and M Spies, A. (2023) Allosteric Tuning of Caspase-7: Establishing the Nexus of Structure and Catalytic Power. Chemistry. 29, e202300872

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