Publications
Biochemical and biophysical characterization of natural polyreactivity in antibodies. Cell Rep. 42, 113190
(2023) Cancer-associated somatic mutations in human phosphofructokinase-1 reveal a critical electrostatic interaction for allosteric regulation of enzyme activity. Biochem J. 480, 1411-1427
(2023) cGLRs are a diverse family of pattern recognition receptors in innate immunity. Cell. 186, 3261-3276.e20
(2023) Co-crystal structures of the fluorogenic aptamer Beetroot show that close homology may not predict similar RNA architecture. Nat Commun. 14, 2969
(2023) Crystal structure of LGR ligand α2/β5 from with implications for the evolution of glycoprotein hormones.. Proc Natl Acad Sci U S A. 120, e2218630120
(2023) De novo design of high-affinity binders of bioactive helical peptides. Nature. 10.1038/s41586-023-06953-1
(2023) Development and atomic structure of a new fluorescence-based sensor to probe heme transfer in bacterial pathogens. J Inorg Biochem. 249, 112368
(2023) Directing polymorph specific calcium carbonate formation with de novo protein templates. Nat Commun. 14, 8191
(2023) (2023) DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity. bioRxiv. 10.1101/2023.03.06.531355
(2023) (2023) Emergence of a proton exchange-based isomerization and lactonization mechanism in the plant coumarin synthase COSY. Nat Commun. 14, 597
(2023) Epstein-Barr Virus Encoded BCL2, BHRF1, Downregulates Autophagy by Noncanonical Binding of BECN1. Biochemistry. 62, 2934-2951
(2023) A Fluorescence Polarization Assay for Macrodomains Facilitates the Identification of Potent Inhibitors of the SARS-CoV-2 Macrodomain. ACS Chem Biol. 18, 1200-1207
(2023) Hallucination of closed repeat proteins containing central pockets. Nat Struct Mol Biol. 30, 1755-1760
(2023) High-resolution structures with bound Mn and Cd map the metal import pathway in an Nramp transporter. Elife. 10.7554/eLife.84006
(2023) Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc Natl Acad Sci U S A. 120, e2214556120
(2023) Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc Natl Acad Sci U S A. 120, e2214556120
(2023) Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc Natl Acad Sci U S A. 120, e2214556120
(2023) Improving the secretion of designed protein assemblies through negative design of cryptic transmembrane domains. Proc Natl Acad Sci U S A. 120, e2214556120
(2023) Inhibition of talin-induced integrin activation by a double-hit stapled peptide. Structure. 31, 948-957.e3
(2023) Insight into the mechanism of H-coupled nucleobase transport. Proc Natl Acad Sci U S A. 120, e2302799120
(2023) Insight into the mechanism of H-coupled nucleobase transport. Proc Natl Acad Sci U S A. 120, e2302799120
(2023) (2023) (2023)