Publications
S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.. Mol Cell. 65, 699-714.e6
(2017) RWD domain: a recurring module in kinetochore architecture shown by a Ctf19-Mcm21 complex structure. EMBO Rep. 13, 216-22
(2012) (2013) Rules for the design of aza-glycine stabilized triple-helical collagen peptides. Chem Sci. 11, 10638-10646
(2020) (R)-Profens are substrate-selective inhibitors of endocannabinoid oxygenation by COX-2. Nat Chem Biol. 7, 803-9
(2011) ROR and RYK extracellular region structures suggest that receptor tyrosine kinases have distinct WNT-recognition modes. Cell Rep. 37, 109834
(2021) Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase. Biochemistry. 48, 6423-30
(2009) Role of the Pif1-PCNA Complex in Pol δ-Dependent Strand Displacement DNA Synthesis and Break-Induced Replication.. Cell Rep. 21, 1707-1714
(2017) A role of the Lowe syndrome protein OCRL in early steps of the endocytic pathway. Dev Cell. 13, 377-90
(2007) The role of nonconserved residues of Archaeoglobus fulgidus ferritin on its unique structure and biophysical properties. J Biol Chem. 288, 32663-72
(2013) The role of distant mutations and allosteric regulation on LovD active site dynamics. Nat Chem Biol. 10, 431-6
(2014) Role of arginine 293 and glutamine 288 in communication between catalytic and allosteric sites in yeast ribonucleotide reductase. J Mol Biol. 419, 315-29
(2012) The role of 9-O-acetylated glycan receptor moieties in the typhoid toxin binding and intoxication. PLoS Pathog. 16, e1008336
(2020) RNase L-activating 2'-5' oligoadenylates bind ABCF1, ABCF3 and Decr-1. J Gen Virol. 10.1099/jgv.0.001890
(2023) RNA stabilization by a poly(A) tail 3'-end binding pocket and other modes of poly(A)-RNA interaction. Science. 10.1126/science.abe6523
(2021) (2006) (2017) RNA ligase structures reveal the basis for RNA specificity and conformational changes that drive ligation forward. Cell. 127, 71-84
(2006) The rippled β-sheet layer configuration-a novel supramolecular architecture based on predictions by Pauling and Corey.. Chem Sci. 13, 8947-8952
(2022) Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4.. Chem Res Toxicol. 26, 1348-60
(2013) A RING E3-substrate complex poised for ubiquitin-like protein transfer: structural insights into cullin-RING ligases. Nat Struct Mol Biol. 18, 947-9
(2011) RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex. Proc Natl Acad Sci U S A. 112, 5272-9
(2015) RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.. Cell Rep. 12, 788-97
(2015) Rigidification Dramatically Improves Inhibitor Selectivity for RAF Kinases. ACS Med Chem Lett. 10, 1074-1080
(2019) (2018)